View source for ALDH1B1

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Aldehyde dehydrogenase X, mitochondrial''' is an [[enzyme]] that in humans is encoded by the ''ALDH1B1'' [[gene]].<ref name="pmid2061311">{{cite journal | vauthors = Hsu LC, Chang WC | title = Cloning and characterization of a new functional human aldehyde dehydrogenase gene | journal = The Journal of Biological Chemistry | volume = 266 | issue = 19 | pages = 12257–65 | date = Jul 1991 | doi = 10.1016/S0021-9258(18)98890-3 | pmid = 2061311 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: ALDH1B1 aldehyde dehydrogenase 1 family, member B1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=219}}</ref>
== Function ==
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.<ref name="entrez"/>
== References ==
{{reflist|33em}}
==External links==
* {{UCSC gene info|ALDH1B1}}
== Further reading ==
{{refbegin|33em}}
* {{cite journal | vauthors = Yoshida A | title = Molecular genetics of human aldehyde dehydrogenase | journal = Pharmacogenetics | volume = 2 | issue = 4 | pages = 139–47 | date = Aug 1992 | pmid = 1306115 | doi = 10.1097/00008571-199208000-00001 }}
* {{cite journal | vauthors = Hiraoka LR, Hsu L, Hsieh CL | title = Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13 | journal = Genomics | volume = 25 | issue = 1 | pages = 323–5 | date = Jan 1995 | pmid = 7774944 | doi = 10.1016/0888-7543(95)80150-K }}
* {{cite journal | vauthors = Stewart MJ, Malek K, Xiao Q, Dipple KM, Crabb DW | title = The novel aldehyde dehydrogenase gene, ALDH5, encodes an active aldehyde dehydrogenase enzyme | journal = Biochemical and Biophysical Research Communications | volume = 211 | issue = 1 | pages = 144–51 | date = Jun 1995 | pmid = 7779080 | doi = 10.1006/bbrc.1995.1789 }}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = Jan 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
* {{cite journal | vauthors = Sherman D, Davé V, Hsu LC, Peters TJ, Yoshida A | title = Diverse polymorphism within a short coding region of the human aldehyde dehydrogenase-5 (ALDH5) gene | journal = Human Genetics | volume = 92 | issue = 5 | pages = 477–80 | date = Nov 1993 | pmid = 8244338 | doi = 10.1007/BF00216454 | s2cid = 10507521 }}
* {{cite journal | vauthors = Stewart MJ, Malek K, Crabb DW | title = Distribution of messenger RNAs for aldehyde dehydrogenase 1, aldehyde dehydrogenase 2, and aldehyde dehydrogenase 5 in human tissues | journal = Journal of Investigative Medicine | volume = 44 | issue = 2 | pages = 42–6 | date = Feb 1996 | pmid = 8689400 }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = Oct 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
* {{cite journal | vauthors = Luo P, Wang A, Payne KJ, Peng H, Wang JG, Parrish YK, Rogerio JW, Triche TJ, He Q, Wu L | title = Intrinsic retinoic acid receptor alpha-cyclin-dependent kinase-activating kinase signaling involves coordination of the restricted proliferation and granulocytic differentiation of human hematopoietic stem cells | journal = Stem Cells | volume = 25 | issue = 10 | pages = 2628–37 | date = Oct 2007 | pmid = 17628022 | doi = 10.1634/stemcells.2007-0264 | s2cid = 20497224 | doi-access = free }}
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{{Aldehyde dehydrogenases}}
{{gene-9-stub}}