View source for Aldose-6-phosphate reductase (NADPH)

{{infobox enzyme
| Name       = aldose-6-phosphate reductase (NADPH)
| EC_number  = 1.1.1.200
| CAS_number = 76901-04-7
| GO_code    = 0047641
| image      =
| width      =
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In [[enzymology]], an '''aldose-6-phosphate reductase (NADPH)''' ({{EC number|1.1.1.200}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
:D-sorbitol 6-phosphate + NADP<sup>+</sup> <math>\rightleftharpoons</math> D-glucose 6-phosphate + NADPH + H<sup>+</sup>
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[D-sorbitol 6-phosphate]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[D-glucose 6-phosphate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is '''D-aldose-6-phosphate:NADP<sup>+</sup> 1-oxidoreductase'''. Other names in common use include '''aldose 6-phosphate reductase''', '''NADP<sup>+</sup>-dependent aldose 6-phosphate reductase''', '''A6PR''', '''aldose-6-P reductase''', '''aldose-6-phosphate reductase''', '''alditol 6-phosphate:NADP<sup>+</sup> 1-oxidoreductase''', and '''aldose-6-phosphate reductase (NADPH)'''.
==References==
{{reflist|1}}
* {{cite journal | vauthors = Negm FB, Loescher WH | date = 1981 | title = Characterization and partial-purification of aldose-6-phosphate reductase (alditol-6-phosphate-NADP 1-oxidoreductase) from apple leaves | journal = Plant Physiol. | volume = 67 | pages = 139&ndash;142 | doi = 10.1104/pp.67.1.139 | pmc = 425637 | pmid=16661614}}
{{Alcohol oxidoreductases}}
{{Enzymes}}
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[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]
{{1.1.1-enzyme-stub}}