View source for Aquamid

{{Short description|Injectable cosmetic filler}}
'''Aquamid''' is a non-absorbable soft volume filler for aesthetic and reconstructive purposes. Aquamid is the trade name for a specific formulation of 97.5% water for injection and 2.5% cross-linked [[polyacrylamide]]. It is injected [[subcutaneous tissue|subcutaneously]] to correct [[wrinkle]]s and folds or to add volume. Common aesthetic indications are [[nasolabial folds]], [[lip enhancement|lip augmentation]], cheek contouring, nose enhancement. Aquamid is also used to correct signs of facial lipoatrophy or fat wasting in HIV+ patients.<ref>Contura International, {{cite web|title=Treating facial lipoatrophy |url=http://www.aquamid.com/fl/patient |url-status=dead |archiveurl=https://web.archive.org/web/20110904060748/http://www.aquamid.com/fl/patient |archivedate=2011-09-04 }}</ref>
Aquamid has been evaluated in several [[clinical trial]]s<ref name="pmid20517105">{{cite journal|vauthors=Pallua N, Wolter TP | title=A 5-year assessment of safety and aesthetic results after facial soft-tissue augmentation with polyacrylamide hydrogel (Aquamid): a prospective multicenter study of 251 patients. | journal=Plast Reconstr Surg | year= 2010 | volume= 125 | issue= 6 | pages= 1797–804 | pmid=20517105 | doi=10.1097/PRS.0b013e3181d18158| s2cid=9807073 }}</ref><ref name="pmid19116518">{{cite journal|vauthors=Yagi Y, Kato K, Murakami D, Misaki K, Ota M | title=Utilization of aquamid as a filler for rhinoplasty in orientals. | journal=Plast Reconstr Surg | year= 2009 | volume= 123 | issue= 1 | pages= 26e–28e | pmid=19116518 | doi=10.1097/PRS.0b013e318194d1e9 | doi-access=free }}</ref><ref name="pmid19320569">{{cite journal|vauthors=Negredo E, Puig J, Aldea D, Medina M, Estany C, Pérez-Alvarez N | title=Four-year safety with polyacrylamide hydrogel to correct antiretroviral-related facial lipoatrophy. | journal=AIDS Res Hum Retroviruses | year= 2009 | volume= 25 | issue= 4 | pages= 451–5 | pmid=19320569 | doi=10.1089/aid.2008.0230|display-authors=etal}}</ref> involving more than 5,000 patients including a comparative trial in the United States. Data from this trial has been used to support a PMA application to the [[Food and Drug Administration|FDA]]. Aquamid is not yet approved for sale in the United States.
Aquamid is developed, produced and commercialized by [[Contura International]].<ref>Contura International, {{cite web|title=Aquamid product page |url=http://contura.com/products/aquamid}}</ref> It was approved in Europe in 2001 for facial augmentation and minor body contouring and is available in several countries in Europe, Asia, the Middle East and Latin America.
==References==
{{reflist}}
==External links==
* [http://www.aquamid.com/ Aquamid Website]
[[Category:Plastic surgery filler]]
[[Category:Acrylate polymers]]
[[Category:Polyelectrolytes]]
[[Category:Gels]]