View source for BW284C51

{{Chembox
| Name = BW284C51
| ImageFile = BW284C51.svg
| PIN = 4,4′-(3-Oxopentane-1,5-diyl)bis[''N'',''N''-dimethyl-''N''-(prop-2-en-1-yl)anilinium] dibromide
| OtherNames =
| Section1 = {{Chembox Identifiers
| CASNo = 402-40-4
| ChemSpiderID = 9437
| PubChem = 9820
| ChEMBL = 464538
| SMILES = C[N+](C)(CC=C)c1ccc(cc1)CCC(=O)CCc2ccc(cc2)[N+](C)(C)CC=C.[Br-].[Br-]
| StdInChI = InChI=1S/C27H38N2O.2BrH/c1-7-21-28(3,4)25-15-9-23(10-16-25)13-19-27(30)20-14-24-11-17-26(18-12-24)29(5,6)22-8-2;;/h7-12,15-18H,1-2,13-14,19-22H2,3-6H3;2*1H/q+2;;/p-2
| StdInChIKey = WKDURMTZOWGWTD-UHFFFAOYSA-L
}}
| Section2 = {{Chembox Properties
| C=27|H=38|Br=2|N=2|O=1
}}
| Section3 = {{Chembox Hazards
| MainHazards = Toxic
| GHSPictograms = {{GHS06}}
| GHSSignalWord = Danger
| HPhrases = {{H-phrases|300|310|330}}
| PPhrases = {{P-phrases|260|262|264|270|271|280|284|301+310|302+350|304+340|310|320|321|322|330|361|363|403+233|405|501}}
}}
}}
'''BW284C51''' is a selective [[acetylcholinesterase inhibitor]].<ref>{{cite journal |last1=FULTON |first1=MP |last2=MOGEY |first2=GA |title=Some selective inhibitors of true cholinesterase. |journal=British Journal of Pharmacology and Chemotherapy |date=June 1954 |volume=9 |issue=2 |pages=138–44 |doi=10.1111/j.1476-5381.1954.tb00832.x |pmid=13172421 |pmc=1509427}}</ref> It is also a [[nicotinic antagonist]].<ref>{{cite journal |last1=Olivera-Bravo |first1=S |last2=Ivorra |first2=I |last3=Morales |first3=A |title=The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane. |journal=British Journal of Pharmacology |date=January 2005 |volume=144 |issue=1 |pages=88–97 |doi=10.1038/sj.bjp.0705965 |pmid=15644872 |pmc=1575971}}</ref>
==See also==
*[[Cholinesterase inhibitor]]
*[[Nicotinic antagonist]]
==References==
{{reflist}}
{{Acetylcholine metabolism and transport modulators}}
{{Nicotinic acetylcholine receptor modulators}}
[[Category:Acetylcholinesterase inhibitors]]
[[Category:Quaternary ammonium compounds]]
[[Category:Ketones]]
[[Category:Allyl compounds]]
[[Category:Bromides]]
[[Category:Bisquaternary anticholinesterases]]
{{Pharma-stub}}