View source for Carotenoid-9',10'-cleaving dioxygenase

{{Infobox enzyme
| Name       = Carotenoid-9',10'-cleaving dioxygenase
| EC_number  = 1.13.11.71
| CAS_number =
| GO_code    =
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}}
'''Carotenoid-9',10'-cleaving dioxygenase''' ({{EC number|1.13.11.71}}, ''BCO2 (gene)'', ''beta-carotene 9',10'-monooxygenase (misleading)'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''all-trans-beta-carotene:O<sub>2</sub> oxidoreductase (9',10'-cleaving)''.<ref>{{cite journal | vauthors = Kiefer C, Hessel S, Lampert JM, Vogt K, Lederer MO, Breithaupt DE, von Lintig J | title = Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A | journal = The Journal of Biological Chemistry | volume = 276 | issue = 17 | pages = 14110–6 | date = April 2001 | pmid = 11278918 | doi = 10.1074/jbc.M011510200 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Lindqvist A, He YG, Andersson S | title = Cell type-specific expression of beta-carotene 9',10'-monooxygenase in human tissues | journal = The Journal of Histochemistry and Cytochemistry | volume = 53 | issue = 11 | pages = 1403–12 | date = November 2005 | pmid = 15983114 | doi = 10.1369/jhc.5A6705.2005 | doi-access = free }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
: all-trans-beta-carotene + O<sub>2</sub> <math>\rightleftharpoons</math> all-trans-10'-apo-beta-carotenal + [[beta-ionone]]
Carotenoid-9',10'-cleaving dioxygenase contains Fe<sup>2+</sup>.
== References ==
{{reflist}}
== External links ==
* {{MeshName|Carotenoid-9',10'-cleaving+dioxygenase}}
{{Monooxygenases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}
[[Category:EC 1.13.11]]