View source for Complement receptor of the immunoglobulin family

{{Short description|Protein family}}
{{protein
| Name = V-set and immunoglobulin domain containing 4
| caption =
| image =
| width =
| HGNCid = 17032
| Symbol = VSIG4
| AltSymbols =
| EntrezGene = 11326
| OMIM = 300353
| RefSeq = NM_007268
| UniProt = Q9Y279
| PDB =
| ECnumber =
| Chromosome = X
| Arm = q
| Band = 12
| LocusSupplementaryData = -q13.3
}}
'''Complement receptor of the immunoglobulin family''' is a [[protein]] expressed in [[Kupffer cell]]s.<ref>{{cite journal | vauthors = Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M | title = CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens | journal = Cell | volume = 124 | issue = 5 | pages = 915–27 | year = 2006 | pmid = 16530040 | doi = 10.1016/j.cell.2005.12.039| doi-access = free }}</ref> It is a critical receptor for the [[phagocytosis]] of [[Opsonin|opsonised]] particles in the [[blood]]. It recognizes [[iC3b]] (inactivated C3b) deposited on microbial surfaces.
==See also==
* [[complement system]]
* [[immunoglobulin]]
==References==
<references/>
{{gene-X-stub}}