View source for Crotonoyl-(acyl-carrier-protein) hydratase

{{Orphan|date=September 2019}}
{{infobox enzyme
| Name       = crotonoyl-[acyl-carrier-protein] hydratase
| EC_number  = 4.2.1.58
| CAS_number = 9030-78-8
| GO_code    = 0047450
| image      =
| width      =
| caption    =
}}
In [[enzymology]], a '''crotonoyl-[acyl-carrier-protein] hydratase''' ({{EC number|4.2.1.58}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
:(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] <math>\rightleftharpoons</math> but-2-enoyl-[acyl-carrier-protein] + H<sub>2</sub>O
Hence, this enzyme has one [[substrate (biochemistry)|substrate]], [[(3R)-3-hydroxybutanoyl-[acyl-carrier-protein]]], and two [[product (chemistry)|products]], [[but-2-enoyl-[acyl-carrier-protein]]] and [[water|H<sub>2</sub>O]].
This enzyme belongs to the family of [[lyase]]s, specifically the hydro-lyases, which cleave carbon-oxygen bonds.  The [[List of enzymes|systematic name]] of this enzyme class is '''(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming)'''. Other names in common use include '''(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase''', '''beta-hydroxybutyryl acyl carrier protein dehydrase''', '''beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase''', '''beta-hydroxybutyryl acyl carrier protein dehydrase''', '''enoyl acyl carrier protein hydrase''', '''crotonyl acyl carrier protein hydratase''', '''3-hydroxybutyryl acyl carrier protein dehydratase''', '''beta-hydroxybutyryl acyl carrier''', and '''protein dehydrase'''.  This enzyme participates in [[fatty acid biosynthesis]].
==References==
{{reflist|1}}
* {{cite journal | vauthors = MAJERUS PW, ALBERTS AW, VAGELOS PR | date = 1965 | title = ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS | journal = J. Biol. Chem.  | volume = 240 | pages = 618&ndash;21  | pmid = 14275113 }}
* {{cite journal | vauthors = Mizugaki M, Weeks G, Toomey RE, Wakil SJ | date = 1968 | title = Studies on the mechanism of fatty acid synthesis. XX. Preparation and general properties of beta-hydroxybutyryl acyl carrier protein dehydrase | journal = J. Biol. Chem.  | volume = 243 | pages = 3661&ndash;70  | pmid = 5658542 | issue = 13 }}
{{Carbon-oxygen lyases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}
[[Category:EC 4.2.1]]
[[Category:Enzymes of unknown structure]]
{{4.2-enzyme-stub}}