View source for D-lysopine dehydrogenase

{{infobox enzyme
| Name       = D-lysopine dehydrogenase
| EC_number  = 1.5.1.16
| CAS_number = 65187-41-9
| GO_code    = 0047827
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In [[enzymology]], a '''D-lysopine dehydrogenase''' ({{EC number|1.5.1.16}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
:N<sub>2</sub>-(D-1-carboxyethyl)-L-lysine + NADP<sup>+</sup> + H<sub>2</sub>O <math>\rightleftharpoons</math> L-lysine + pyruvate + NADPH + H<sup>+</sup>
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[N2-(D-1-carboxyethyl)-L-lysine]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]], whereas its 4 [[product (chemistry)|products]] are [[L-lysine]], [[pyruvate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor.  The [[List of enzymes|systematic name]] of this enzyme class is '''N2-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase (L-lysine-forming)'''. Other names in common use include '''D-lysopine synthase''', '''lysopine dehydrogenase''', '''D(+)-lysopine dehydrogenase''', '''2-N-(D-1-carboxyethyl)-L-lysine:NADP+ oxidoreductase''', and '''(L-lysine-forming)'''.  This enzyme participates in [[lysine degradation]].
==References==
{{reflist|1}}
* {{cite journal | vauthors = Otten LA, Vreugdenhil D, Schilperoort RA | date = 1977 | title = Properties of D(+)-lysopine dehydrogenase from crown gall tumour tissue | journal = Biochim. Biophys. Acta  | volume = 485 | pages = 268&ndash;77  | pmid = 21695 | issue = 2 | doi=10.1016/0005-2744(77)90163-2}}
{{CH-NH oxidoreductases}}
{{Enzymes}}
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[[Category:EC 1.5.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]
{{1.5-enzyme-stub}}