View source for DTDP-galactose 6-dehydrogenase

{{Short description|Class of enzymes}}
{{DISPLAYTITLE:dTDP-galactose 6-dehydrogenase}}
{{infobox enzyme
| Name       = DTDP-galactose 6-dehydrogenase
| EC_number  = 1.1.1.186
| CAS_number =
| GO_code    =
| image      =
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}}
In [[enzymology]], a '''dTDP-galactose 6-dehydrogenase''' ({{EC number|1.1.1.186}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
:dTDP-D-galactose + 2 NADP<sup>+</sup> + H<sub>2</sub>O <math>\rightleftharpoons</math> dTDP-D-galacturonate + 2 NADPH + 2 H<sup>+</sup>
The 3 [[substrate (biochemistry)|substrates]] of this enzyme are [[dTDP-D-galactose]], [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], and [[water|H<sub>2</sub>O]], whereas its 3 [[product (chemistry)|products]] are [[dTDP-D-galacturonate]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is '''dTDP-D-galactose:NADP<sup>+</sup> 6-oxidoreductase'''. This enzyme is also called '''thymidine-diphosphate-galactose dehydrogenase'''. This enzyme participates in [[nucleotide sugars metabolism]].
==References==
{{reflist|1}}
* {{cite journal |vauthors=Katan R, Avigad G | date = 1966 | title = NADP dependent oxidation of TDP-glucose by an enzyme system from sugar beets | journal = Biochem. Biophys. Res. Commun. | volume = 24 | pages = 18&ndash;24 | pmid = 4381717 | doi = 10.1016/0006-291X(66)90403-7 | issue = 1 }}
{{Alcohol oxidoreductases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}
[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]
{{1.1.1-enzyme-stub}}