View source for EPS8L1

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Epidermal growth factor receptor kinase substrate 8-like protein 1''' is an [[enzyme]] that in humans is encoded by the ''EPS8L1'' [[gene]].<ref name="pmid12620401">{{cite journal | vauthors = Tocchetti A, Confalonieri S, Scita G, Di Fiore PP, Betsholtz C | title = In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure | journal = Genomics | volume = 81 | issue = 2 | pages = 234–44 |date=Mar 2003 | pmid = 12620401 | doi =10.1016/S0888-7543(03)00002-8  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EPS8L1 EPS8-like 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54869}}</ref>
This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 ([[EPS8]]), a substrate for the [[epidermal growth factor receptor]]. The function of this protein is unknown. Several alternatively spliced [[transcript variants]] encoding different [[isoforms]] exist.<ref name="entrez" />
==References==
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==Further reading==
{{refbegin | 2}}
*{{cite journal  | vauthors=Kimura K, Wakamatsu A, Suzuki Y |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406  | pmc=1356129 |display-authors=etal}}
*{{cite journal  | vauthors=Wan D, Gong Y, Qin W |title=Large-scale cDNA transfection screening for genes related to cancer development and progression |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 44 |pages= 15724–9 |year= 2004 |pmid= 15498874 |doi= 10.1073/pnas.0404089101  | pmc=524842 |bibcode=2004PNAS..10115724W |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Offenhäuser N, Borgonovo A, Disanza A |title=The eps8 Family of Proteins Links Growth Factor Stimulation to Actin Reorganization Generating Functional Redundancy in the Ras/Rac Pathway |journal=Mol. Biol. Cell |volume=15 |issue= 1 |pages= 91–8 |year= 2004 |pmid= 14565974 |doi= 10.1091/mbc.E03-06-0427  | pmc=307530 |display-authors=etal}}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |display-authors=etal|doi-access=free }}
*{{cite journal  | vauthors=Wu K, Xu Z, Wang M |title=[Cloning and expression analyses of down-regulated cDNA C6-2A in human esophageal cancer] |journal=Zhonghua Yi Xue Yi Chuan Xue Za Zhi |volume=16 |issue= 5 |pages= 325–7 |year= 1999 |pmid= 10514543 |display-authors=etal}}
{{refend}}
{{PDB Gallery|geneid=54869}}
{{gene-19-stub}}