View source for FKBP10

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''FK506-binding protein 10''' is a [[protein]] that in humans is encoded by the ''FKBP10'' [[gene]].<ref name="pmid11071917">{{cite journal |vauthors=Patterson CE, Schaub T, Coleman EJ, Davis EC | title = Developmental Regulation of FKBP65: An ER-localized Extracellular Matrix Binding-Protein | journal = Mol Biol Cell | volume = 11 | issue = 11 | pages = 3925–35 |date=Feb 2001 | pmid = 11071917 | pmc = 15047 | doi =  10.1091/mbc.11.11.3925}}</ref><ref name="pmid18786928">{{cite journal |vauthors=Ishikawa Y, Vranka J, Wirz J, Nagata K, Bachinger HP | title = The rough endoplasmic reticulum-resident FK506-binding protein FKBP65 is a molecular chaperone that interacts with collagens | journal = J Biol Chem | volume = 283 | issue = 46 | pages = 31584–90 |date=Nov 2008 | pmid = 18786928 | doi = 10.1074/jbc.M802535200 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: FKBP10 FK506 binding protein 10, 65 kDa| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=60681}}</ref>
The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl [[Cis-acting|cis]]/[[Trans-acting|trans]] [[isomerase]] family. It is located in [[endoplasmic reticulum]] and acts as molecular chaperones. Two [[Splice variant|alternatively spliced variants]], which encode different [[isoform]], are reported.<ref name="entrez" />
==References==
{{Reflist}}
==Further reading==
{{refbegin | 2}}
* {{cite journal  |vauthors=Patterson CE, Gao J, Rooney AP, Davis EC |title=Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family |journal=Genomics |volume=79 |issue= 6 |pages= 881–9 |year= 2002 |pmid= 12036304 |doi= 10.1006/geno.2002.6777 }}
* {{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-style=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
* {{cite journal  |vauthors=Zhang H, Li XJ, Martin DB, Aebersold R |title=Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry |journal=Nat. Biotechnol. |volume=21 |issue= 6 |pages= 660–6 |year= 2003 |pmid= 12754519 |doi= 10.1038/nbt827 |s2cid=581283 }}
* {{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285  |name-list-style=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki | doi-access=free  }}
* {{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-style=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
* {{cite journal  | author=Otsuki T |title=Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries |journal=DNA Res. |volume=12 |issue= 2 |pages= 117–26 |year= 2007 |pmid= 16303743 |doi= 10.1093/dnares/12.2.117  |name-list-style=vanc| author2=Ota T  | author3=Nishikawa T  | display-authors=3  | last4=Hayashi  | first4=K  | last5=Suzuki  | first5=Y  | last6=Yamamoto  | first6=J  | last7=Wakamatsu  | first7=A  | last8=Kimura  | first8=K  | last9=Sakamoto  | first9=K | doi-access=free  }}
* {{cite journal  | author=Foster LJ |title=Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC) |journal=J. Proteome Res. |volume=5 |issue= 1 |pages= 64–75 |year= 2006 |pmid= 16396496 |doi= 10.1021/pr0502626  |name-list-style=vanc| author2=Rudich A  | author3=Talior I  | display-authors=3  | last4=Patel  | first4=Nish  | last5=Huang  | first5=Xudong  | last6=Furtado  | first6=L. Michelle  | last7=Bilan  | first7=Philip J.  | last8=Mann  | first8=Matthias  | last9=Klip  | first9=Amira }}
{{refend}}
{{Geometric isomerases}}
{{Enzymes}}
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[[Category:EC 5.2.1]]
[[Category:EF-hand-containing proteins]]
{{Gene-17-stub}}