View source for Genotype–phenotype map

{{Short description|Conceptual model in genetic architecture}}
[[File:SimpleGenotypePhenotypeMap.jpg|alt=Genotype-Phenotype Map|thumb|A very simple genotype–phenotype map that only shows additive pleiotropy effects.]]
The '''genotype–phenotype map''' is a conceptual model in [[genetic architecture]]. Coined in a 1991 paper by [[Pere Alberch]],<ref>{{cite journal |url=https://link.springer.com/article/10.1007/BF00123979 |title=From genes to phenotype: dynamical systems and evolvability |last1=Alberch |first1=Pere |journal=Genetica |year=1991 |volume=84 |issue=1 |pages=5–11 |doi=10.1007/BF00123979 |pmid=1874440 |s2cid=28286781 |access-date=18 October 2020}}</ref> it models the interdependency of [[genotype]] (an organism's full [[hereditary]] information) with [[phenotype]] (an organism's actual observed properties).
==Application==
The map visualises a relationship between genotype & phenotype which, crucially:<ref>{{cite journal |title=Genotype–phenotype mapping and the end of the 'genes as blueprint' metaphor |last1=Pigliucci |first1=Massimo |journal=Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences |year=2010 |volume=365 |issue=1540 |pages=557–566 |doi=10.1098/rstb.2009.0241 |pmid=20083632 |pmc=2817137 }}</ref>
# is of greater complexity than a straightforward one-to-one mapping of genotype to/from phenotype.
# accommodates a [[parameter space]], along which at different points a given phenotype is said to be more or less stable.
# accommodates [[Transform fault|transformational boundaries]] in the parameter space, which divide [[Phenotypic trait|phenotype states]] from one another.
# accounts for different [[Gene polymorphism|polymorphism]] and/or [[polyphenism]] in populations, depending on their area of parameter space they occupy.
== See also ==
* [[Genotype–phenotype distinction]]
==References==
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[[Category:Genetics]]
[[Category:1991 introductions]]