View source for Genous

'''Genous''' is an [[endothelial progenitor cell]] (EPC) capture technology manufactured by [[OrbusNeich]] that promotes the accelerated natural healing of the vessel wall after [[stent]] implantation. The pro-healing technology has an [[antibody]] surface coating that captures circulating [[CD34]]+ [[endothelial progenitor cell]]s to the device, forming a functional [[endothelium|endothelial]] layer over the [[stent]] to protect against [[thrombus]] and minimize [[restenosis]].<ref>Bylander, Jessica (27 October 2008). "New Stents On The Block: Innovators Look Beyond Drug Coatings." The Gray Sheet.</ref><ref>[http://www.healio.com/cardiology/vascular-medicine/news/print/cardiology-today/%7Bc4490368-d6db-457e-b9b2-ce6786b1ebc4%7D/novel-stent-promotes-healing-of-vessel-wall-after-implantation "Novel stent promotes healing of vessel wall after implantation"] Cardiology Today</ref>
The Genous Stent is a bio-engineered [[coronary stent]] coated with immobilized anti-CD34 monoclonal antibodies specific to the Genous technology.<ref>{{cite journal |vauthors=Klomp M, Beijk MA, de Winter RJ |date=July 2009 |title=Genous™ endothelial progenitor cell-capturing stent system: a novel stent technology |journal=Expert Review of Medical Devices |volume=6 |issue=4 |pages=365–375 |accessdate=28 August 2012 |url=http://www.expert-reviews.com/doi/abs/10.1586/erd.09.16?prevSearch=allfield%253A%2528genous%2529&searchHistoryKey= |doi=10.1586/erd.09.16|pmid=19572791 |s2cid=22534986 }}</ref><ref>[http://www.cxvascular.com/cn-latest-news/cardiovascular-news---latest-news/genous-stent-is-a-safe-and-effective-option-in-stemi-patients- "Genous stent is a safe and effective option in STEMI patients"] {{Webarchive|url=https://web.archive.org/web/20131029201027/http://www.cxvascular.com/cn-latest-news/cardiovascular-news---latest-news/genous-stent-is-a-safe-and-effective-option-in-stemi-patients- |date=2013-10-29 }} Cardiovascular News International</ref>
The [[Dual therapy stent|Combo Dual Therapy Stent]] is a [[coronary stent]] that combines Genous with an antiproliferative, biodegradable [[sirolimus]] drug elution. The Combo Stent was shown to be as effective as a [[paclitaxel]]-eluting stent in controlling [[Neointimal Hyperplasia]].<ref>London, Susan (14 November 2011). "Bioengineered, Sirolimus-Eluting Stent Found ‘Safe,’ and ‘Effective.’" Cardiology News.</ref><ref>[http://www.healio.com/cardiology/intervention/news/print/cardiology-today-intervention/%7Bd6561e10-c5c0-4c9d-afbd-f65922406b27%7D/dual-therapy-stenting-the-next-step-in-the-evolution-of-stent-design- "Dual-Therapy Stenting: The Next Step in the Evolution of Stent Design"] Cardiology Today: Intervention</ref><ref>[http://www.medpagetoday.com/MeetingCoverage/TCT/29632 "TCT: Combo Stent Comparable to Taxus"] MedPage Today</ref>
== References ==
{{Reflist}}
== External links ==
* [http://www.orbusneich.com/ OrbusNeich Web site]
[[Category:Implants (medicine)]]