View source for Glucose 1-dehydrogenase (NADP+)

{{DISPLAYTITLE:Glucose 1-dehydrogenase (NADP<sup>+</sup>)}}
{{infobox enzyme
| Name       = glucose 1-dehydrogenase (NADP<sup>+</sup>)
| EC_number  = 1.1.1.119
| CAS_number = 37250-50-3
| GO_code    = 0047935
| image      =
| width      =
| caption    =
}}
In [[enzymology]], a '''glucose 1-dehydrogenase (NADP<sup>+</sup>)''' ({{EC number|1.1.1.119}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
:D-glucose + NADP<sup>+</sup> <math>\rightleftharpoons</math> D-glucono-1,5-lactone + NADPH + H<sup>+</sup>
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[D-glucose]] and [[nicotinamide adenine dinucleotide phosphate|NADP<sup>+</sup>]], whereas its 3 [[product (chemistry)|products]] are [[Glucono delta-lactone|D-glucono-1,5-lactone]], [[nicotinamide adenine dinucleotide phosphate|NADPH]], and [[hydrogen ion|H<sup>+</sup>]].
This enzyme belongs to the family of [[oxidoreductase]]s, specifically those acting on the CH-OH group of donor with NAD<sup>+</sup> or NADP<sup>+</sup> as acceptor. The [[List of enzymes|systematic name]] of this enzyme class is '''D-glucose:NADP<sup>+</sup> 1-oxidoreductase'''. Other names in common use include '''nicotinamide adenine dinucleotide phosphate-linked aldohexose''', '''dehydrogenase''', '''NADP<sup>+</sup>-linked aldohexose dehydrogenase''', '''NADP<sup>+</sup>-dependent glucose dehydrogenase''', and '''glucose 1-dehydrogenase (NADP<sup>+</sup>)'''.
==References==
{{reflist|1}}
* {{cite book |author1 = Adachi O |author2 =Ameyama M |chapter =D-Glucose dehydrogenase from Gluconobacter su☐ydans | date = 1982 | title = Carbohydrate Metabolism - Part D | volume = 89 | pages = 159&ndash;163 | doi = 10.1016/S0076-6879(82)89028-9 | series = Methods in Enzymology | isbn = 978-0-12-181989-7 }}
* {{cite journal | vauthors = Avigad G, Alroy Y, Englard S | date = 1968 | title = Purification and properties of a nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogeanse from ''Gluconobacter cerinus'' | journal = J. Biol. Chem. | volume = 243 | pages = 1936&ndash;41 | pmid = 4384672 | issue = 8 | doi = 10.1016/S0021-9258(18)93531-3 | doi-access = free }}
{{Alcohol oxidoreductases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}
[[Category:EC 1.1.1]]
[[Category:NADPH-dependent enzymes]]
[[Category:Enzymes of unknown structure]]
{{1.1.1-enzyme-stub}}