View source for KHSRP

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Far upstream element-binding protein 2''' is a [[protein]] that in humans is encoded by the ''KHSRP'' [[gene]].<ref name="pmid9136930">{{cite journal |vauthors=Min H, Turck CW, Nikolic JM, Black DL | title = A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer | journal = Genes Dev | volume = 11 | issue = 8 | pages = 1023–36 |date=May 1997 | pmid = 9136930 | doi =10.1101/gad.11.8.1023  | doi-access = free }}</ref><ref name="pmid8940189">{{cite journal |vauthors=Davis-Smyth T, Duncan RC, Zheng T, Michelotti G, Levens D | title = The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators | journal = J Biol Chem | volume = 271 | issue = 49 | pages = 31679–87 |date=Jan 1997 | pmid = 8940189 | doi =10.1074/jbc.271.49.31679  | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KHSRP KH-type splicing regulatory protein (FUSE binding protein 2)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8570}}</ref>
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
*{{cite journal  |vauthors=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317–20 |year= 1992 |pmid= 1602151 |doi=10.1016/S0163-4453(05)80037-4  }}
*{{cite journal  |vauthors=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=10.1101/gr.6.9.791  |doi-access=free }}
*{{cite journal  |vauthors=Chou MY, Rooke N, Turck CW, Black DL |title=hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells. |journal=Mol. Cell. Biol. |volume=19 |issue= 1 |pages= 69–77 |year= 1999 |pmid= 9858532 |doi=  10.1128/MCB.19.1.69| pmc=83866  }}
*{{cite journal   |vauthors=Ring HZ, Vameghi-Meyers V, Nikolic JM, etal |title=Mapping of the KHSRP gene to a region of conserved synteny on human chromosome 19p13.3 and mouse chromosome 17. |journal=Genomics |volume=56 |issue= 3 |pages= 350–2 |year= 1999 |pmid= 10087204 |doi= 10.1006/geno.1998.5725 |doi-access= free }}
*{{cite journal   |vauthors=Lellek H, Kirsten R, Diehl I, etal |title=Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex. |journal=J. Biol. Chem. |volume=275 |issue= 26 |pages= 19848–56 |year= 2000 |pmid= 10781591 |doi= 10.1074/jbc.M001786200 |doi-access= free }}
*{{cite journal   |vauthors=Chou MY, Underwood JG, Nikolic J, etal |title=Multisite RNA binding and release of polypyrimidine tract binding protein during the regulation of c-src neural-specific splicing. |journal=Mol. Cell |volume=5 |issue= 6 |pages= 949–57 |year= 2000 |pmid= 10911989 |doi=10.1016/S1097-2765(00)80260-9  |doi-access=free }}
*{{cite journal   |vauthors=Markovtsov V, Nikolic JM, Goldman JA, etal |title=Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein. |journal=Mol. Cell. Biol. |volume=20 |issue= 20 |pages= 7463–79 |year= 2000 |pmid= 11003644 |doi=10.1128/MCB.20.20.7463-7479.2000  | pmc=86300  }}
*{{cite journal   |vauthors=Chen CY, Gherzi R, Ong SE, etal |title=AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. |journal=Cell |volume=107 |issue= 4 |pages= 451–64 |year= 2002 |pmid= 11719186 |doi=10.1016/S0092-8674(01)00578-5  |s2cid=14817671 |doi-access=free }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
*{{cite journal  |vauthors=Hall MP, Huang S, Black DL |title=Differentiation-induced colocalization of the KH-type splicing regulatory protein with polypyrimidine tract binding protein and the c-src pre-mRNA. |journal=Mol. Biol. Cell |volume=15 |issue= 2 |pages= 774–86 |year= 2004 |pmid= 14657238 |doi= 10.1091/mbc.E03-09-0692  | pmc=329392 }}
*{{cite journal   |vauthors=Gherzi R, Lee KY, Briata P, etal |title=A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery. |journal=Mol. Cell |volume=14 |issue= 5 |pages= 571–83 |year= 2004 |pmid= 15175153 |doi= 10.1016/j.molcel.2004.05.002 |doi-access= free }}
*{{cite journal   |vauthors=Suswam EA, Nabors LB, Huang Y, etal |title=IL-1beta induces stabilization of IL-8 mRNA in malignant breast cancer cells via the 3' untranslated region: Involvement of divergent RNA-binding factors HuR, KSRP and TIAR. |journal=Int. J. Cancer |volume=113 |issue= 6 |pages= 911–9 |year= 2005 |pmid= 15514971 |doi= 10.1002/ijc.20675 |s2cid=33272692 |doi-access=free }}
*{{cite journal   |vauthors=Wickham L, Benjannet S, Marcinkiewicz E, etal |title=Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin. |journal=J. Neurochem. |volume=92 |issue= 1 |pages= 93–102 |year= 2005 |pmid= 15606899 |doi= 10.1111/j.1471-4159.2004.02840.x |s2cid=36799858 |doi-access=free }}
*{{cite journal   |vauthors=Chou CF, Mulky A, Maitra S, etal |title=Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decay. |journal=Mol. Cell. Biol. |volume=26 |issue= 10 |pages= 3695–706 |year= 2006 |pmid= 16648466 |doi= 10.1128/MCB.26.10.3695-3706.2006  | pmc=1489004 }}
*{{cite journal   |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |s2cid=14294292 }}
*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |s2cid=7827573 |doi-access=free }}
*{{cite journal   |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134  | pmc=1847948 }}
{{refend}}
{{PDB Gallery|geneid=8570}}
{{gene-19-stub}}