View source for MSRB2

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Methionine-R-sulfoxide reductase B2, mitochondrial''' is an [[enzyme]] that in humans is encoded by the ''MSRB2'' [[gene]].<ref name="pmid8749308">{{cite journal |vauthors=Escribano J, Ortego J, Coca-Prados M | title = Isolation and characterization of cell-specific cDNA clones from a subtractive library of the ocular ciliary body of a single normal human donor: transcription and synthesis of plasma proteins | journal = J Biochem | volume = 118 | issue = 5 | pages = 921–31 |date=Jan 1997 | pmid = 8749308 | doi =  10.1093/jb/118.5.921}}</ref><ref name="pmid10375640">{{cite journal |vauthors=Huang W, Escribano J, Sarfarazi M, Coca-Prados M | title = Identification, expression and chromosome localization of a human gene encoding a novel protein with similarity to the pilB family of transcriptional factors (pilin) and to bacterial peptide methionine sulfoxide reductases | journal = Gene | volume = 233 | issue = 1–2 | pages = 233–40 |date=Aug 1999 | pmid = 10375640 | doi =10.1016/S0378-1119(99)00131-6  | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MSRB2 methionine sulfoxide reductase B2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=22921}}</ref> The MRSB2 enzyme catalyzes the [[redox|reduction]] of [[Methionine oxidation|methionine sulfoxide]] to [[methionine]].
==See also==
*[[MSRA (gene)]]
*[[Methionine oxidation]]
*[[SEPX1]]
==References==
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==Further reading==
{{refbegin | 2}}
*{{cite journal   |vauthors=Lai CH, Chou CY, Ch'ang LY, etal |title=Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics |journal=Genome Res. |volume=10 |issue= 5 |pages= 703–13 |year= 2000 |pmid= 10810093 |doi=10.1101/gr.10.5.703  | pmc=310876  }}
*{{cite journal   |vauthors=Jung S, Hansel A, Kasperczyk H, etal |title=Activity, tissue distribution and site-directed mutagenesis of a human peptide methionine sulfoxide reductase of type B: hCBS1 |journal=FEBS Lett. |volume=527 |issue= 1–3 |pages= 91–4 |year= 2002 |pmid= 12220640 |doi=10.1016/S0014-5793(02)03171-X  |s2cid=2170229 |doi-access=free }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
*{{cite journal  |vauthors=Kim HY, Gladyshev VN |title=Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases |journal=Mol. Biol. Cell |volume=15 |issue= 3 |pages= 1055–64 |year= 2004 |pmid= 14699060 |doi= 10.1091/mbc.E03-08-0629  | pmc=363075 }}
*{{cite journal   |vauthors=Picot CR, Perichon M, Cintrat JC, etal |title=The peptide methionine sulfoxide reductases, MsrA and MsrB (hCBS-1), are downregulated during replicative senescence of human WI-38 fibroblasts |journal=FEBS Lett. |volume=558 |issue= 1–3 |pages= 74–8 |year= 2004 |pmid= 14759519 |doi= 10.1016/S0014-5793(03)01530-8 |s2cid=32573388 }}
*{{cite journal  |vauthors=Hansel A, Jung S, Hoshi T, Heinemann SH |title=A second human methionine sulfoxide reductase (hMSRB2) reducing methionine-R-sulfoxide displays a tissue expression pattern distinct from hMSRB1 |journal=Redox Rep. |volume=8 |issue= 6 |pages= 384–8 |year= 2004 |pmid= 14980072 |doi= 10.1179/135100003225003429 |doi-access= free }}
*{{cite journal   |vauthors=[[Karin Schallreuter|Schallreuter KU]], Rübsam K, Chavan B, etal |title=Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus |journal=Biochem. Biophys. Res. Commun. |volume=342 |issue= 1 |pages= 145–52 |year= 2006 |pmid= 16480945 |doi= 10.1016/j.bbrc.2006.01.124 }}
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