View source for MTMR9

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Myotubularin-related protein 9''' is a [[protein]] that in humans is encoded by the ''MTMR9'' [[gene]].<ref name="pmid11472061">{{cite journal | vauthors = Appel S, Reichwald K, Zimmermann W, Reis A, Rosenthal A, Hennies HC | title = Identification and localization of a new human myotubularin-related protein gene, mtmr8, on 8p22-p23 | journal = Genomics | volume = 75 | issue = 1–3 | pages = 6–8  | date = Jul 2001 | pmid = 11472061 | doi = 10.1006/geno.2001.6591 }}</ref><ref name="pmid11896452">{{cite journal | vauthors = Appel S, Filter M, Reis A, Hennies HC, Bergheim A, Ogilvie E, Arndt S, Simmons A, Lovett M, Hide W, Ramsay M, Reichwald K, Zimmermann W, Rosenthal A | title = Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759 | journal = Eur. J. Hum. Genet. | volume = 10 | issue = 1 | pages = 17–25  | date = Mar 2002 | pmid = 11896452 | doi = 10.1038/sj.ejhg.5200750 | doi-access = free }}</ref><ref name="pmid12890864">{{cite journal | vauthors = Mochizuki Y, Majerus PW | title = Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9 | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 100 | issue = 17 | pages = 9768–73  | date = Aug 2003 | pmid = 12890864 | pmc = 187840 | doi = 10.1073/pnas.1333958100 | bibcode = 2003PNAS..100.9768M | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MTMR9 myotubularin related protein 9| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=66036}}</ref>
== Function ==
This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.<ref name="entrez" />
== Interactions ==
MTMR9 has been shown to [[Protein-protein interaction|interact]] with [[MTMR6]].<ref name=pmid12890864 />
== References ==
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== Further reading ==
{{refbegin | 2}}
* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | year = 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
* {{cite journal | vauthors = Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA | title = A "double adaptor" method for improved shotgun library construction | journal = Anal. Biochem. | volume = 236 | issue = 1 | pages = 107–13 | year = 1996 | pmid = 8619474 | doi = 10.1006/abio.1996.0138 }}
* {{cite journal | vauthors = Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA | title = Large-scale concatenation cDNA sequencing | journal = Genome Res. | volume = 7 | issue = 4 | pages = 353–8 | year = 1997 | pmid = 9110174 | pmc = 139146 | doi = 10.1101/gr.7.4.353 }}
* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | year = 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
* {{cite journal | vauthors = Wang JC, Radford DM, Holt MS, Helms C, Goate A, Brandt W, Parik M, Phillips NJ, DeSchryver K, Schuh ME, Fair KL, Ritter JH, Marshall P, Donis-Keller H | title = Sequence-ready contig for the 1.4-cM ductal carcinoma in situ loss of heterozygosity region on chromosome 8p22-p23 | journal = Genomics | volume = 60 | issue = 1 | pages = 1–11 | year = 1999 | pmid = 10458905 | doi = 10.1006/geno.1999.5905 }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M |author-link30=Huda Zoghbi| title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | year = 2005 | pmid = 16189514 | doi = 10.1038/nature04209 |bibcode=2005Natur.437.1173R|s2cid=4427026}}
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{{Protein tyrosine phosphatases}}
{{gene-8-stub}}