View source for OR8B8

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Olfactory receptor 8B8''' is a [[protein]] that in humans is encoded by the ''OR8B8'' [[gene]].<ref name="pmid9119360">{{cite journal | vauthors = Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M | title = Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species | journal = Genomics | volume = 39 | issue = 3 | pages = 239–46 |date=Apr 1997 | pmid = 9119360 | doi = 10.1006/geno.1996.4490 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: OR8B8 olfactory receptor, family 8, subfamily B, member 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=26493}}</ref>
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" />
==See also==
* [[Olfactory receptor]]
==References==
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==Further reading==
{{refbegin | 2}}
*{{cite journal  | vauthors=Gaudin JC, Breuils L, Haertlé T |title=New GPCRs from a human lingual cDNA library |journal=Chem. Senses |volume=26 |issue= 9 |pages= 1157–66 |year= 2002 |pmid= 11705801 |doi=10.1093/chemse/26.9.1157  |doi-access= }}
*{{cite journal   |vauthors=Fuchs T, Malecova B, Linhart C, etal |title=DEFOG: a practical scheme for deciphering families of genes |journal=Genomics |volume=80 |issue= 3 |pages= 295–302 |year= 2003 |pmid= 12213199 |doi=10.1006/geno.2002.6830  |url=http://www.cs.tau.ac.il/~roded/defog.pdf }}
*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993  |bibcode=2004PNAS..101.2584M |doi-access=free }}
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== External links ==
* {{MeshName|OR8B8+protein,+human}}
{{NLM content}}
{{Olfactory receptors}}
[[Category:Olfactory receptors]]
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