View source for Rideal–Walker coefficient

{{Short description|Disinfecting power of a disinfectant}}
The '''Rideal–Walker coefficient''', now only of historical interest,<ref name=baxby>{{cite journal|last=Baxby|first=Derrick|author-link = Derrick Baxby|title=3. The Chick–Martin test for disinfectants|journal=Epidemiol. Infect.|date=2005|volume=133|issue=Suppl. 1|pages=S13–14|doi=10.1017/s0950268805004231|pmid=24965238|doi-access=free}}</ref>  is a figure expressing the disinfecting power of any disinfectant. It is the ratio of the  dilution of the [[disinfectant]] that kills a [[microorganism]] to the dilution of phenol that kills the organism in the same time under identical conditions. The Rideal–Walker coefficient determines the [[phenol coefficient]] utilizing the method (test)  described by English chemists Samuel Rideal (1863–1929) and J. T. Ainslie Walker (1868–1930).<ref>{{cite journal|last=Rideal|first=S.|author2=Walker, J. T. A. |title=The standardisation of disinfectants|journal=J. R. Sanit. Inst.|date=1903|volume=24|issue=3|pages=424–441|doi=10.1177/146642400302400320|url=https://zenodo.org/record/1448694/files/article.pdf}}</ref>
The arbitrary choice of contact time (sterilisation in 7.5 minutes), [[diluent]] (distilled water) and test organism ([[Salmonella typhi]], then called Bacillus typhosa) did not reflect the conditions under which disinfectants were used. Because of this, impossibly high values were obtained for disinfectant activity and quoted by disinfectant manufacturers. The method was referred to by distinguished microbiologist Sir Ashley Miles as  "...at best a grossly over-simplified answer to a very difficult problem, and at worst little short of bacteriological prostitution".<ref>{{cite book|last=Miles|first=A. A.|title=Topley and Wilson's principles of bacteriology and immunity, vol. 1|date=1946|publisher=Arnold|location=London|page=148|edition=3rd|editor1=Wilson, G. S. |editor2=Miles, A. A.}}</ref>
It was replaced by a  more realistic test devised by Dame [[Harriette Chick]] and [[Sir Charles James Martin]],<ref>{{cite journal |last1=Chick |first1=Harriette |last2=Martin |first2=C. |title=The principles involved in the standardization of disinfectants and the influence of organic matter upon germicidal value |journal=J. Hyg. |date=1908 |volume=8 |issue=5 |pages=654–97 |pmid=20474377 |pmc=2167170 |doi=10.1017/s0022172400016016}}</ref> which in turn was replaced by other tests, not reliant on a comparison with phenol, in attempts to assess the effectiveness of particular disinfectants for different purposes.<ref name=baxby/>
== See also ==
*[[Phenol coefficient]]
== References ==
{{reflist}}
* [http://medical-dictionary.thefreedictionary.com/Rideal-Walker+coefficient Rideal-Walker coefficient.]  Retrieved Nov. 6, 2006.
{{DEFAULTSORT:Rideal-Walker coefficient}}
[[Category:Disinfectants]]