View source for SEPSECS

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''O-phosphoseryl-tRNA(Sec) selenium transferase''' is an [[enzyme]] that in humans is encoded by the ''SEPSECS'' [[gene]].<ref name="pmid16230358">{{cite journal | vauthors = Xu XM, Mix H, Carlson BA, Grabowski PJ, Gladyshev VN, Berry MJ, Hatfield DL | title = Evidence for direct roles of two additional factors, SECp43 and soluble liver antigen, in the selenoprotein synthesis machinery | journal = J. Biol. Chem. | volume = 280 | issue = 50 | pages = 41568–75  | date = Dec 2005 | pmid = 16230358 | doi = 10.1074/jbc.M506696200 | doi-access = free | url = https://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1058&context=biochemgladyshev }}</ref><ref name="pmid10931155">{{cite journal | vauthors = Costa M, Rodríguez-Sánchez JL, Czaja AJ, Gelpí C | title = Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP(Ser)Sec complex recognized by autoantibodies from patients with type-1 autoimmune hepatitis | journal = Clin. Exp. Immunol. | volume = 121 | issue = 2 | pages = 364–74  | date = Aug 2000 | pmid = 10931155 | pmc = 1905695 | doi = 10.1046/j.1365-2249.2000.01280.x }}</ref><ref name="pmid17142313">{{cite journal | vauthors = Yuan J, Palioura S, Salazar JC, Su D, O'Donoghue P, Hohn MJ, Cardoso AM, Whitman WB, Söll D | title = RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 103 | issue = 50 | pages = 18923–7  | date = Dec 2006 | pmid = 17142313 | pmc = 1748153 | doi = 10.1073/pnas.0609703104 | bibcode = 2006PNAS..10318923Y | doi-access = free }}</ref><ref name="pmid17194211">{{cite journal | vauthors = Xu XM, Carlson BA, Mix H, Zhang Y, Saira K, Glass RS, Berry MJ, Gladyshev VN, Hatfield DL | title = Biosynthesis of selenocysteine on its tRNA in eukaryotes | journal = PLOS Biol. | volume = 5 | issue = 1 | pages = e4  | date = Apr 2007 | pmid = 17194211 | pmc = 1717018 | doi = 10.1371/journal.pbio.0050004 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLA/LP soluble liver antigen/liver pancreas antigen| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51091}}</ref>
== References ==
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== Further reading ==
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* {{cite journal | vauthors = Herkel J, Heidrich B, Nieraad N, Wies I, Rother M, Lohse AW | title = Fine specificity of autoantibodies to soluble liver antigen and liver/pancreas | journal = Hepatology | volume = 35 | issue = 2 | pages = 403–8 | year = 2002 | pmid = 11826415 | doi = 10.1053/jhep.2002.30699 | s2cid = 46400743 | doi-access = free }}
* {{cite journal | vauthors = Volkmann M, Martin L, Bäurle A, Heid H, Strassburg CP, Trautwein C, Fiehn W, Manns MP | title = Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis | journal = Hepatology | volume = 33 | issue = 3 | pages = 591–6 | year = 2001 | pmid = 11230739 | doi = 10.1053/jhep.2001.22218 | s2cid = 11978013 | doi-access = free }}
* {{cite journal | vauthors = Wies I, Brunner S, Henninger J, Herkel J, Kanzler S, Meyer zum Büschenfelde KH, Lohse AW | title = Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis | journal = Lancet | volume = 355 | issue = 9214 | pages = 1510–5 | year = 2000 | pmid = 10801173 | doi = 10.1016/S0140-6736(00)02166-8 | s2cid = 45159673 }}
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