View source for TAC3

{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Infobox_gene}}
'''Tachykinin-3''' is a [[protein]] that in humans is encoded by the ''TAC3'' [[gene]].<ref name="pmid3479225">{{cite journal |vauthors=Bonner TI, Affolter HU, Young AC, Young WS  | title = A cDNA encoding the precursor of the rat neuropeptide, neurokinin B | journal = Brain Res | volume = 388 | issue = 3 | pages = 243–9 |date=Jan 1988 | pmid = 3479225 | doi =  10.1016/0169-328x(87)90031-3}}</ref><ref name="pmid10866201">{{cite journal |vauthors=Page NM, Woods RJ, Gardiner SM, Lomthaisong K, Gladwell RT, Butlin DJ, Manyonda IT, Lowry PJ | title = Excessive placental secretion of neurokinin B during the third trimester causes pre-eclampsia | journal = Nature | volume = 405 | issue = 6788 | pages = 797–800 |date=Jul 2000 | pmid = 10866201 | doi = 10.1038/35015579 | bibcode = 2000Natur.405..797P | s2cid = 4392048 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TAC3 tachykinin 3 (neuromedin K, neurokinin beta)| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6866}}</ref>
==See also==
*[[Neurokinin B]]
*[[Tachykinin receptor 3]]
==References==
{{reflist}}
==Further reading==
{{refbegin | 2}}
*{{cite journal  |vauthors=Page NM, Woods RJ, Lowry PJ |title=A regulatory role for neurokinin B in placental physiology and pre-eclampsia. |journal=Regul. Pept. |volume=98 |issue= 3 |pages= 97–104 |year= 2001 |pmid= 11231038 |doi=10.1016/S0167-0115(00)00239-1  |s2cid=7160887 }}
*{{cite journal  |vauthors=Rance NE, Young WS |title=Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women. |journal=Endocrinology |volume=128 |issue= 5 |pages= 2239–47 |year= 1991 |pmid= 1708331 |doi=10.1210/endo-128-5-2239  }}
*{{cite journal  |vauthors=Bhogal N, Donnelly D, Findlay JB |title=The ligand binding site of the neurokinin 2 receptor. Site-directed mutagenesis and identification of neurokinin A binding residues in the human neurokinin 2 receptor. |journal=J. Biol. Chem. |volume=269 |issue= 44 |pages= 27269–74 |year= 1994 |doi=10.1016/S0021-9258(18)46979-7 |pmid= 7961636 |doi-access=free }}
*{{cite journal  |vauthors=Tian Y, Wu LH, Oxender DL, Chung FZ |title=The unpredicted high affinities of a large number of naturally occurring tachykinins for chimeric NK1/NK3 receptors suggest a role for an inhibitory domain in determining receptor specificity. |journal=J. Biol. Chem. |volume=271 |issue= 34 |pages= 20250–7 |year= 1996 |pmid= 8702757 |doi=10.1074/jbc.271.34.20250  |doi-access=free }}
*{{cite journal  | author=Krause JE |title=Functional expression of a novel human neurokinin-3 receptor homolog that binds 3Hsenktide and 125I-MePhe7neurokinin B, and is responsive to tachykinin peptide agonists |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 1 |pages= 310–5 |year= 1997 |pmid= 8990205 |doi=10.1073/pnas.94.1.310  | pmc=19326  |name-list-style=vanc| author2=Staveteig PT  | author3=Mentzer JN  | display-authors=3  | last4=Schmidt  | first4=SK  | last5=Tucker  | first5=JB  | last6=Brodbeck  | first6=RM  | last7=Bu  | first7=JY  | last8=Karpitskiy  | first8=VV  |doi-access=free }}
*{{cite journal  |vauthors=Brunelleschi S, Bordin G, Colangelo D, Viano I |title=Tachykinin receptors on human monocytes: their involvement in rheumatoid arthritis |journal=Neuropeptides |volume=32 |issue= 3 |pages= 215–23 |year= 1999 |pmid= 10189055 |doi=10.1016/S0143-4179(98)90040-3  |s2cid=40222022 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241  |name-list-style=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD |bibcode=2002PNAS...9916899M |doi-access=free }}
*{{cite journal  | author=Brownbill P |title=Neurokinin B is a paracrine vasodilator in the human fetal placental circulation |journal=J. Clin. Endocrinol. Metab. |volume=88 |issue= 5 |pages= 2164–70 |year= 2003 |pmid= 12727971 |doi=10.1210/jc.2002-021727  |name-list-style=vanc| author2=Bell NJ  | author3=Woods RJ  | display-authors=3  | last4=Lowry  | first4=PJ  | last5=Page  | first5=NM  | last6=Sibley  | first6=CP  | doi-access=free  }}
*{{cite journal  | author=Clark HF |title=The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003  | pmc=403697  |name-list-style=vanc| author2=Gurney AL  | author3=Abaya E  | display-authors=3  | last4=Baker  | first4=K  | last5=Baldwin  | first5=D  | last6=Brush  | first6=J  | last7=Chen  | first7=J  | last8=Chow  | first8=B  | last9=Chui  | first9=C }}
*{{cite journal  | author=Schlembach D |title=Neurokinin B peptide serum levels are higher in normotensive pregnant women than in preeclamptic pregnant women |journal=Am. J. Obstet. Gynecol. |volume=189 |issue= 5 |pages= 1418–22 |year= 2003 |pmid= 14634580 |doi=10.1067/S0002-9378(03)00775-0  |name-list-style=vanc| author2=Scalera F  | author3=Fischer T  | display-authors=3  | last4=Marx  | first4=Stephen G  | last5=Beinder  | first5=Ernst  | last6=Garfield  | first6=Robert E  }}
*{{cite journal  |vauthors=Laliberte C, DiMarzo L, Morrish DW, Kaufman S |title=Neurokinin B causes concentration-dependent relaxation of isolated human placental resistance vessels |journal=Regul. Pept. |volume=117 |issue= 2 |pages= 123–6 |year= 2004 |pmid= 14700748 |doi=10.1016/j.regpep.2003.10.032  |s2cid=25577867 }}
*{{cite journal  | author=Pal S |title=Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1 |journal=J. Biol. Chem. |volume=279 |issue= 30 |pages= 31348–56 |year= 2004 |pmid= 15123623 |doi= 10.1074/jbc.M403475200  |name-list-style=vanc| author2=Nemeth MJ  | author3=Bodine D  | display-authors=3  | last4=Miller  | first4=JL  | last5=Svaren  | first5=J  | last6=Thein  | first6=SL  | last7=Lowry  | first7=PJ  | last8=Bresnick  | first8=EH | doi-access=free  }}
*{{cite journal  |vauthors=Mantha AK, Chandrashekar IR, Baquer NZ, Cowsik SM |title=Three dimensional structure of mammalian tachykinin peptide neurokinin B bound to lipid micelles |journal=J. Biomol. Struct. Dyn. |volume=22 |issue= 2 |pages= 137–48 |year= 2005 |pmid= 15317475 |doi=  10.1080/07391102.2004.10506990|s2cid=41064499 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928  |name-list-style=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  |vauthors=Page NM, Dakour J, Morrish DW |title=Gene regulation of neurokinin B and its receptor NK3 in late pregnancy and pre-eclampsia |journal=Mol. Hum. Reprod. |volume=12 |issue= 7 |pages= 427–33 |year= 2006 |pmid= 16709596 |doi= 10.1093/molehr/gal025 |doi-access= free }}
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