View source for TOX2

{{Short description|Mammalian protein found in Homo sapiens}}
{{infobox protein
| Name = TOX high mobility group box family member 2
| caption =
| image =
| width =
| HGNCid = 16095
| Symbol = TOX2
| AltSymbols = C20orf100, GCX-1
| EntrezGene = 84969
| OMIM = 611163
| RefSeq = NM_001098796
| UniProt = Q96NM4
| PDB =
| ECnumber =
| Chromosome = 20
| Arm = q
| Band = 13.12
| LocusSupplementaryData =
}}
'''TOX high mobility group box family member 2''', also known as '''TOX2''', is a human [[gene]].<ref name="entrez_84969">{{cite web | title = Entrez Gene: TOX high mobility group box family member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=84969}}</ref><ref name="pmid14764631">{{cite journal | vauthors = Kajitani T, Mizutani T, Yamada K, Yazawa T, Sekiguchi T, Yoshino M, Kawata H, Miyamoto K | title = Cloning and characterization of granulosa cell high-mobility group (HMG)-box protein-1, a novel HMG-box transcriptional regulator strongly expressed in rat ovarian granulosa cells | journal = Endocrinology | volume = 145 | issue = 5 | pages = 2307–18 |date=May 2004 | pmid = 14764631 | doi = 10.1210/en.2003-1343 | s2cid = 25037508 | doi-access =  }}</ref>
The [[protein]] encoded by this gene is a member of a subfamily of [[transcription factor]]s that also includes [[TOX]], [[TOX3]], and [[TOX4]] that share almost identical [[HMG-box]] [[DNA-binding domain]]s which function to modify [[chromatin]] structure.<ref name="pmid12697058">{{cite journal | vauthors = O'Flaherty E, Kaye J | title = TOX defines a conserved subfamily of HMG-box proteins | journal = BMC Genomics | volume = 4 | pages = 13 |date=April 2003 | issue = 1 | pmid = 12697058 | pmc = 155677 | doi = 10.1186/1471-2164-4-13 | doi-access = free }}</ref>
==References==
{{Reflist}}
{{Transcription factors|g4}}
[[Category:Transcription factors]]
{{gene-20-stub}}