View source for Testosterone propionate/testosterone enanthate/testosterone undecylenate

{{Short description|Combination drug}}
{{Drugbox
<!--Combo data-->
| type = combo
| drug_name = TP/TE/TUe
| component1 = Testosterone propionate
| class1 = [[Androgen]]; [[Anabolic steroid]]
| component2 = Testosterone enanthate
| class2 = [[Androgen]]; [[Anabolic steroid]]
| component3 = Testosterone undecylenate
| class3 = [[Androgen]]; [[Anabolic steroid]]
<!-- Clinical data -->
| tradename = Durasteron
| Drugs.com =
| MedlinePlus =
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
| pregnancy_US = <!-- A / B / C / D / X -->
| pregnancy_category =
| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
| legal_CA = <!-- OTC, Rx-only, Schedule I, II, III, IV, V, VI, VII, VIII -->
| legal_UK = <!-- GSL, P, POM, CD, CD Lic, CD POM, CD No Reg POM, CD (Benz) POM, CD (Anab) POM or CD Inv POM -->
| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
| legal_status =
| routes_of_administration = [[Intramuscular injection]]
<!-- Identifiers -->
| CAS_number =
| ATC_prefix =
| ATC_suffix =
| PubChem =
| DrugBank =
| synonyms = TP/TE/TUe
}}
'''Testosterone propionate/testosterone enanthate/testosterone undecylenate''' ('''TP/TE/TUe'''), sold under the brand name '''Durasteron''', is an [[injection (medicine)|injectable]] [[combination drug|combination medication]] of [[testosterone propionate]] (TP), [[testosterone valerate]] (TV), and [[testosterone undecylenate]] (TUe), all of which are [[androgen]]s/[[anabolic steroid]]s.<ref name="DaherSilva Júnior2009" /><ref name="Davani-DavariKarimzadeh2019" /> It contains 20&nbsp;mg TP, 80&nbsp;mg TE, and 150&nbsp;mg TUe (for a total of 250&nbsp;mg [[testosterone ester]] and 169.5&nbsp;mg free [[testosterone (medication)|testosterone]]) in [[oil solution]] and is administered by [[intramuscular injection]] at regular intervals, for instance once every 3 or 4&nbsp;weeks.<ref name="Joël1960">{{cite journal| vauthors = Joël CA |title=Zur Behandlung männlicher Fertilitätsstörungen mit hohen Androgendosen|trans-title=For the treatment of male fertility disorders with high androgen doses|journal=Gynecologic and Obstetric Investigation|volume=150|issue=3|year=1960|pages=149–156|issn=1423-002X|doi=10.1159/000305737|quote=[...] 20 mg Testosteronpropionat, 80 mg Testosteronheptanoat, 150 mg Testosteronundecylat (Durasteron Teva) [...] }}</ref><ref name="ArendsZörnig2013">{{cite book| vauthors = Arends G, Zörnig H, Hager H, Frerichs G, Kern W |title=Hagers Handbuch der pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Drogisten, Ärzte u. Medizinalbeamte|url=https://books.google.com/books?id=8bLwBgAAQBAJ&pg=PA1145|date=14 December 2013|publisher=Springer-Verlag|isbn=978-3-662-36329-4|pages=1145–|quote=At the same time, treatment with a long-acting testosterone preparation (Durasteron®) was instituted, with one injection given every four weeks.}}</ref><ref name="SpitzHirsch2014">{{cite journal | vauthors = Spitz IM, Hirsch HJ, Landau H, Zylber-Haran E, Gross V, Rachmilewitz EA | s2cid = 20319052 | title = TSH secretion in thalassemia | journal = Journal of Endocrinological Investigation | volume = 7 | issue = 5 | pages = 495–9 | date = October 1984 | pmid = 6439771 | doi = 10.1007/BF03348456 | quote = The male patients were given a long acting tes- tosterone preparation (Durasteron, Teva) 250 mg by im injection every 3 weeks for a total of 8 injections. }}</ref> Use of Durasteron by [[bodybuilder]]s has been reported.<ref name="DaherSilva Júnior2009">{{cite journal | vauthors = Daher EF, Silva Júnior GB, Queiroz AL, Ramos LM, Santos SQ, Barreto DM, Guimarães AA, Barbosa CA, Franco LM, Patrocínio RM | s2cid = 23319246 | display-authors = 6 | title = Acute kidney injury due to anabolic steroid and vitamin supplement abuse: report of two cases and a literature review | journal = International Urology and Nephrology | volume = 41 | issue = 3 | pages = 717–23 | year = 2009 | pmid = 19387860 | doi = 10.1007/s11255-009-9571-8 }}</ref><ref name="Davani-DavariKarimzadeh2019">{{cite journal | vauthors = Davani-Davari D, Karimzadeh I, Khalili H | title = The potential effects of anabolic-androgenic steroids and growth hormone as commonly used sport supplements on the kidney: a systematic review | journal = BMC Nephrology | volume = 20 | issue = 1 | pages = 198 | date = May 2019 | pmid = 31151420 | doi = 10.1186/s12882-019-1384-0 | pmc = 6545019 | doi-access = free }}</ref>
{{Parenteral durations of androgens/anabolic steroids}}
== See also ==
* [[Testosterone propionate/testosterone valerate/testosterone undecylenate]]
* [[List of combined sex-hormonal preparations#Androgens|List of combined sex-hormonal preparations § Androgens]]
== References ==
{{Reflist}}
{{Androgens and antiandrogens}}
{{Androgen receptor modulators}}
{{DEFAULTSORT:Testosterone propionate testosterone enanthate testosterone undecylenate}}
[[Category:Abandoned drugs]]
[[Category:Combined androgen formulations]]
{{Genito-urinary-drug-stub}}