View source for Ventricular-brain ratio

[[File:Enlarged_lateral_ventricles_in_schizophrenia.png|250px|thumbnail|right|Example of enlarged lateral ventricles in schizophrenia.]]
'''Ventricular-brain ratio (VBR)''', also known as the '''ventricle-to-brain ratio''' or '''ventricle-brain ratio''', is the ratio of total [[Ventricular system|ventricle]] area to total brain area,<ref name="KeatsSistrom2001">{{cite book|author1=Theodore Eliot Keats|author2=Christopher Sistrom|title=Atlas of Radiologic Measurement|url=https://books.google.com/books?id=0ru4vpP4APoC&pg=PA42|year=2001|publisher=Elsevier Health Sciences|isbn=0-323-00161-0|pages=42–}}</ref> which can be calculated with [[planimetry]] from brain imagining techniques such as [[CT scan]]s.<ref><!-- does not work: {{#invoke:Cite | cite | item=Q21100980 }} --> ({{#property:P577|from=Q21100980}}). {{#property:P1476|from=Q21100980}}.  {{#property:P1433|from=Q21100980}}</ref>
It is a common measure of ventricular dilation or cerebral atrophy in patients with [[traumatic brain injury]] or [[hydrocephalus]] ''ex vacuo''.<ref name="ZaslerMD2007">{{cite book|author1=Nathan Zasler|author2=Douglas Katz, MD|author3=Ross D. Zafonte|title=Brain Injury Medicine: Principles and Practice|url=https://books.google.com/books?id=yplFkKimNcYC&pg=PA207|year=2007|publisher=Demos Medical Publishing|isbn=978-1-888799-93-4|pages=207–}}</ref> VBR also tends to increase with age.<ref name="KeatsSistrom2001" />
Generally, a higher VBR means a worse prognosis for recovering from a brain injury.<ref name="ZaslerMD2007">{{cite book|author1=Nathan Zasler|author2=Douglas Katz, MD|author3=Ross D. Zafonte|title=Brain Injury Medicine: Principles and Practice|url=https://books.google.com/books?id=yplFkKimNcYC&pg=PA207|year=2007|publisher=Demos Medical Publishing|isbn=978-1-888799-93-4|pages=207–}}</ref> For example, VBR is significantly correlated with performance on the [[Luria-Nebraska neuropsychological battery]].<ref name="MalateshaHartlage1982">{{cite book|author1=R. N. Malatesha|author2=Lawrence C. Hartlage|title=Neuropsychology and Cognition: Proceedings of the NATO Advanced Study Institute on Neuropsychology and Cognition, Augusta, Georgia, U.S.A., September 8-18, 1980|url=https://books.google.com/books?id=ZOjJGGYXWWEC&pg=PA86|year=1982|publisher=Springer|isbn=978-90-247-2728-5|pages=86}}</ref> Studies have found people with [[schizophrenia]] have larger [[third ventricle]]s and VBR.<ref name="RobinsRutter1990">{{cite book|author1=Lee N. Robins|author2=Michael Rutter|title=Straight and Devious Pathways from Childhood to Adulthood|url=https://books.google.com/books?id=Nc8zAAAAIAAJ&pg=PA333|year=1990|publisher=CUP Archive|isbn=978-0-521-42739-5|pages=333–}}</ref> Correlational studies have found relationships between ventricle-brain ratio and [[binge eating]] and inversely with [[Thyroid hormone|plasma thyroid hormone]] concentration.<ref name="CoffeyBrumback2006">{{cite book|author1=C. Edward Coffey|author2=Roger A. Brumback|title=Pediatric Neuropsychiatry|url=https://books.google.com/books?id=sHDaURMuJ9UC&pg=PA314|year=2006|publisher=Lippincott Williams & Wilkins|isbn=978-0-7817-5191-9|pages=314–}}</ref>
==See also==
* [[Sarnoff A. Mednick]]
* [[Ventriculomegaly]]
==References==
{{reflist}}
[[Category:Behavioral neuroscience]]
{{Psychology stub}}