View source for XhoI

{{Short description|Restriction enzyme}}
{{DISPLAYTITLE:''Xho''I}}
{{Infobox protein family
| Symbol = ''Xho''I
| Name = ''Xho''I
| image =
| width =
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| Pfam = PF04555
| Pfam_clan =
| InterPro = IPR007636
| SMART =
| PROSITE =
| MEROPS =
| SCOP =
| TCDB =
| OPM family =
| OPM protein =
| CAZy =
| CDD =
}}
In [[molecular biology]], '''''Xho''I''' is a type II [[restriction enzymes|restriction enzyme]] [http://expasy.org/enzyme/3.1.21.4 EC] that recognise the double-stranded [[DNA sequence]] CTCGAG and cleaves after C-1.<ref name="pmid3001639">{{cite journal | vauthors = Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF, Gingeras TR | title = Nucleotide sequence of the PaeR7 restriction/modification system and partial characterization of its protein products | journal = Nucleic Acids Res. | volume = 13 | issue = 23 | pages = 8441–61 | date=December 1985 | pmid = 3001639 | pmc = 322144 | doi = 10.1093/nar/13.23.8441}}</ref> Type II [[restriction endonuclease]]s ([http://expasy.org/enzyme/3.1.21.4 EC]) are components of [[prokaryotic]] DNA restriction-modification mechanisms that protect the organism against invading foreign DNA. These site-specific deoxyribonucleases [[catalyse]] the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
==References==
{{reflist}}
{{InterPro content|IPR007636}}
{{restriction enzyme}}
[[Category:Protein families]]
[[Category:Protein domains]]
[[Category:Restriction enzymes]]