In enzymology , a dolichyl-diphosphooligosaccharide–protein glycotransferase (EC 2.4.99.18 ) is an enzyme that catalyzes the chemical reaction
dolichyl diphosphooligosaccharide + protein L-asparagine ⇌ Thus, the two substrates of this enzyme are dolichyl diphosphooligosaccharide and protein L-asparagine , whereas its 3 products are dolichyl diphosphate , glycoprotein with the oligosaccharide chain attached by N-glycosyl , and linkage to protein L-asparagine .
This enzyme belongs to the family of glycosyltransferases , specifically the hexosyltransferases. The systematic name of this enzyme class is dolichyl-diphosphooligosaccharide:protein-L-asparagine oligopolysaccharidotransferase . Other names in common use include dolichyldiphosphooligosaccharide-protein glycosyltransferase , asparagine N-glycosyltransferase , dolichyldiphosphooligosaccharide-protein oligosaccharyltransferase , dolichylpyrophosphodiacetylchitobiose-protein glycosyltransferase , oligomannosyltransferase , oligosaccharide transferase , dolichyldiphosphoryloligosaccharide-protein , and oligosaccharyltransferase . This enzyme participates in n-glycan biosynthesis and glycan structures - biosynthesis 1 .
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Activity Regulation Classification Kinetics Types
