HEPACAM2
An Error has occurred retrieving Wikidata item for infobox HEPACAM family member 2 is a protein that in humans is encoded by the HEPACAM2 gene. [1]
Function
This gene encodes a protein related to the immunoglobulin superfamily that plays a role in mitosis. Knockdown of this gene results in prometaphase arrest, abnormal nuclear morphology, and apoptosis. Poly (ADP-ribosylation) of the encoded protein promotes its translocation to centrosomes, which may stimulate centrosome maturation. A chromosomal deletion including this gene may be associated with myeloid leukemia and myelodysplastic syndrome in human patients.
References
- ↑ "Entrez Gene: HEPACAM family member 2". Retrieved 2017-09-13.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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