The cup was contested by 50 teams. The four Primera División teams that had been semifinalists of Copa de Competencia Británica were automatically entered into the quarter-finals, with other clubs from regional leagues having to qualify to play. Teams were divided into four groups (by province), playing each other in a single round-robin tournament.[1][5]
In quarter finals, San Martín eliminated Boca Juniors (11–9 on the corner kick rule, decision taken after the score remained 2–2 at the end of extra time), then eliminating Sarmiento de Resistencia also on corner kicks (12–7) after a 1–1 tie. On the other hand, Newell's eliminated Bahía Blanca's Villa Mitre after a thrashing 5–0. In semifinals, the Leprossy defeat Talleres de Córdoba 3–1. The final was scheduled to play at Estadio Monumental José Fierro, home venue of San Martín's rival Atlético Tucumán,[4] on March 4, 1945.[5][1] The decision was taken by the Tucumán Football Federation alleging comfort and security reasons.[4]