Springall made her feature film debut in the 2020 Netflix science-fiction drama, The Midnight Sky, directed by George Clooney.[4] In the film, she played the role of Iris, a mysterious young girl who forms a bond with Clooney's character, Augustine Lofthouse. Her performance was widely praised for its emotional depth and maturity, especially considering her young age.[1][5][6]
Following this, Springall secured a main role in the television film Citadel,[7] and a recurring role as Little Girl in the British psychological horror film Stopmotion.[8]
She is set to star in Paul W. S. Anderson's fantasy-adventure film In the Lost Lands, alongside Dave Bautista and Deirdre Mullins, which will be released in 2025.[9] Springall appeared in Doctor Who (2024), playing Splice Alison Vater.[10][11]
In May 2023, it was announced that Caoilinn Springall had joined the cast of The Beast Within, a film adaptation of Edward Levy's 1978 novel of the same name.[12]