OR2W1

From The Right Wiki
Jump to navigationJump to search

An Error has occurred retrieving Wikidata item for infobox Olfactory receptor 2W1 is a protein that in humans is encoded by the OR2W1 gene.[1] Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]

Ligands

Out of 10 human ORs studied, OR2W1 was the most broadly tuned, meaning it responds to the greatest variety of different odorant molecules.[2] Ligands, in decreasing order of sensitivity:[2]

See also

References

  1. Jump up to: 1.0 1.1 "Entrez Gene: OR2W1 olfactory receptor, family 2, subfamily W, member 1".
  2. Jump up to: 2.0 2.1 Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009). "Odor coding by a Mammalian receptor repertoire". Science Signaling. 2 (60): ra9. doi:10.1126/scisignal.2000016. PMC 2774247. PMID 19261596.
  3. Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, et al. (2014). "Identification of odorant-receptor interactions by global mapping of the human odorome". PLOS ONE. 9 (4): e93037. Bibcode:2014PLoSO...993037A. doi:10.1371/journal.pone.0093037. PMC 3973694. PMID 24695519.

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.