SKF-91488
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| File:SKF-91488.svg | |
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| Preferred IUPAC name
4-(Dimethylamino)butyl carbamimidothioate | |
| Identifiers | |
3D model (JSmol)
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| ChEMBL | |
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| Properties | |
| C7H17N3S | |
| Molar mass | 175.29 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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SKF-91488 is a histamine N-methyltransferase inhibitor. It prevents the degradation of histamine, leading to increased histamine levels.[1][2]
See also
References
- ↑ Thakkar, Mahesh M. (February 2011). "Histamine in the regulation of wakefulness". Sleep Medicine Reviews. 15 (1): 65–74. doi:10.1016/j.smrv.2010.06.004. PMC 3016451. PMID 20851648.
- ↑ Tamaoki, J.; Chiyotani, A.; Tagaya, E.; Isono, K.; Konno, K. (1994). "Histamine N-methyltransferase Modulates Human Bronchial Smooth Muscle Contraction". Mediators of Inflammation. 3 (2): 125–129. doi:10.1155/S0962935194000153. PMC 2367027. PMID 18472930.