STK33
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An Error has occurred retrieving Wikidata item for infobox Serine/threonine kinase 33 is a protein that in humans is encoded by the STK33 gene. STK33 was identified as a synthetic lethal gene in KRAS-dependent cell lines.[1] STK33 has been considered as a target for reversible male contraceptives and the inhibitor CDD-2807 has been tested successfully in mice.[2]
References
- ↑ Spoonamore J, Weïwer M, Wei J, Guichard B, Ross NT, Masson K, et al. (2010). "Screen for Inhibitors of STK33 Kinase Activity". Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US). PMID 23658944.
- ↑ "Drug causes reversible male contraception in mice". 10 June 2024.
External links
- STK33+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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