|
---|
ARTooltip Androgen receptor | Agonists |
- Testosterone derivatives: 4-Androstenediol
- 4-Dehydroepiandrosterone (4-DHEA)
- 4-Hydroxytestosterone
- 4,17α-Dimethyltestosterone
- 5-Androstenedione
- 11-Ketotestosterone
- 11β-Hydroxyandrostenedione
- Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione)
- Androstenediol (5-androstenediol)
- Androstenedione (4-androstenedione)
- Atamestane
- Boldenone
- Boldione (1,4-androstadienedione)
- Clostebol
- Cloxotestosterone
- Dehydroandrosterone
- DHEA (androstenolone, prasterone; 5-DHEA)
- Exemestane
- Formestane
- Plomestane
- Quinbolone
- Silandrone
- Testosterone# (+dutasteride)
- 5α-Dihydrotestosterone derivatives: 1-Androstenediol
- 1-Androstenedione
- 1-Androsterone (1-andro, 1-DHEA)
- 1-Testosterone
- 3α-Androstanediol
- 5α-Androst-2-en-17-one
- 7β-Hydroxyepiandrosterone
- 11-Ketodihydrotestosterone
- Androsterone
- Bolazine
- Dihydroethyltestosterone
- Dihydrofluoxymesterone
- Dihydromethylandrostenediol
- Dihydrotestosterone (DHT) (androstanolone, stanolone)
- Drostanolone
- Epiandrosterone
- Epitiostanol
- Mepitiostane
- Mesabolone
- Mesterolone
- Methyldiazinol
- Nisterime
- Prostanozol
- Stenbolone
- Testifenon (testiphenon, testiphenone)
- 19-Nortestosterone derivatives: 7α-Methyl-19-norandrostenedione (MENT dione, trestione)
- 11β-Methyl-19-nortestosterone
- 19-Nor-5-androstenediol
- 19-Nor-5-androstenedione
- 19-Nordehydroepiandrosterone
- Bolandiol
- Bolandione (19-nor-4-androstenedione)
- Bolmantalate (nandrolone adamantoate)
- Dienedione
- Dienolone
- Dimethandrolone
- LS-1727 (nandrolone 17β-N-(2-chloroethyl)-N-nitrosocarbamate)
- Methoxydienone (methoxygonadiene)
- Nandrolone
- Norclostebol
- Normethandrone (methylestrenolone, normethisterone)
- Oxabolone
- Trenbolone
- Trendione
- Trestolone (MENT)
- 5α-Dihydro-19-nortestosterone derivatives: 5α-Dihydronandrolone
- 5α-Dihydrotrestolone
- 19-Norandrosterone
- 17α-Alkylated testosterone derivatives: Bolasterone
- Calusterone
- Chlorodehydromethylandrostenediol (CDMA)
- Chlorodehydromethyltestosterone (CDMT)
- Chloromethylandrostenediol (CMA)
- Enestebol
- Ethyltestosterone
- Fluoxymesterone
- Formebolone
- Hydroxystenozole
- Metandienone (methandrostenolone)
- Methandriol (methylandrostenediol)
- Methylclostebol (chloromethyltestosterone)
- Methyltestosterone (+esterified estrogens)
- Oxymesterone
- Penmesterol
- Tiomesterone
- 17α-Alkylated 5α-dihydrotestosterone derivatives: Androisoxazole
- Desoxymethyltestosterone
- Furazabol
- Mebolazine (dimethazine)
- Mestanolone
- Metenolone
- Methasterone
- Methyl-1-testosterone
- Methylepitiostanol
- Methylstenbolone
- Oxandrolone
- Oxymetholone
- Stanozolol
- 17α-Alkylated 19-nortestosterone derivatives: Bolenol
- Dimethyldienolone
- Dimethyltrienolone
- Ethyldienolone
- Ethylestrenol
- Methyldienolone
- Methylhydroxynandrolone (MOHN, MHN)
- Metribolone
- Mibolerone
- Norboletone
- Norethandrolone
- Propetandrol
- RU-2309
- Tetrahydrogestrinone
- 17α-Alkylated 5α-dihydro-19-nortestosterone derivatives: 5α-Dihydronorethandrolone
- 5α-Dihydronormethandrone
- 17α-Vinyltestosterone derivatives: Norvinisterone (vinylnortestosterone)
- 17α-Vinyl-19-nortestosterone derivatives: Vinyltestosterone
- 17α-Ethynyltestosterone derivatives: Danazol
- Ethinylandrostenediol
- Ethisterone (ethynyltestosterone)
- 5α-Dihydro-17α-ethynyltestosterone derivatives: 17α-Ethynyl-3α-androstanediol
- 17α-Ethynyl-3β-androstanediol
- Dihydroethisterone
- 17α-Ethynyl-19-nortestosterone derivatives: Δ4-Tibolone
- Desogestrel
- Etonogestrel
- Etynodiol
- Gestodene
- Gestrinone
- Levonorgestrel
- Levonorgestrel esters (e.g., levonorgestrel butanoate)
- Lynestrenol
- Norethisterone
- Norethisterone esters (e.g., norethisterone acetate, norethisterone enanthate)
- Norgestrel
- Norgestrienone
- Quingestanol
- Tibolone
- 5α-Dihydro-17α-ethynyl-19-nortestosterone derivatives: 5α-Dihydrolevonorgestrel
- 5α-Dihydronorethisterone
- Progesterone derivatives: 6α-Methylprogesterone
- Medroxyprogesterone acetate
- Megestrol acetate
- Others/unsorted: 3-Keto-5α-abiraterone
- 5α-Androstane
- Alternariol
- Cl-4AS-1
- Drupanol
- Trilostane
- ZM-182345
|
---|
SARMsTooltip Selective androgen receptor modulator | |
---|
Antagonists | |
---|
|
---|
GPRC6A | |
---|
|
|
---|
ERTooltip Estrogen receptor | Agonists |
- Steroidal: 2-Hydroxyestradiol
- 2-Hydroxyestrone
- 3-Methyl-19-methyleneandrosta-3,5-dien-17β-ol
- 3α-Androstanediol
- 3α,5α-Dihydrolevonorgestrel
- 3β,5α-Dihydrolevonorgestrel
- 3α-Hydroxytibolone
- 3β-Hydroxytibolone
- 3β-Androstanediol
- 4-Androstenediol
- 4-Androstenedione
- 4-Fluoroestradiol
- 4-Hydroxyestradiol
- 4-Hydroxyestrone
- 4-Methoxyestradiol
- 4-Methoxyestrone
- 5-Androstenediol
- 7-Oxo-DHEA
- 7α-Hydroxy-DHEA
- 7α-Methylestradiol
- 7β-Hydroxyepiandrosterone
- 8,9-Dehydroestradiol
- 8,9-Dehydroestrone
- 8β-VE2
- 10β,17β-Dihydroxyestra-1,4-dien-3-one (DHED)
- 11β-Chloromethylestradiol
- 11β-Methoxyestradiol
- 15α-Hydroxyestradiol
- 16-Ketoestradiol
- 16-Ketoestrone
- 16α-Fluoroestradiol
- 16α-Hydroxy-DHEA
- 16α-Hydroxyestrone
- 16α-Iodoestradiol
- 16α-LE2
- 16β-Hydroxyestrone
- 16β,17α-Epiestriol (16β-hydroxy-17α-estradiol)
- 17α-Estradiol (alfatradiol)
- 17α-Dihydroequilenin
- 17α-Dihydroequilin
- 17α-Epiestriol (16α-hydroxy-17α-estradiol)
- 17α-Ethynyl-3α-androstanediol
- 17α-Ethynyl-3β-androstanediol
- 17β-Dihydroequilenin
- 17β-Dihydroequilin
- 17β-Methyl-17α-dihydroequilenin
- Abiraterone
- Abiraterone acetate
- Alestramustine
- Almestrone
- Anabolic steroids (e.g., testosterone and esters, methyltestosterone, metandienone (methandrostenolone), nandrolone and esters, many others; via estrogenic metabolites)
- Atrimustine
- Bolandiol
- Bolandiol dipropionate
- Butolame
- Clomestrone
- Cloxestradiol
- Conjugated estriol
- Conjugated estrogens
- Cyclodiol
- Cyclotriol
- DHEA
- DHEA-S
- ent-Estradiol
- Epiestriol (16β-epiestriol, 16β-hydroxy-17β-estradiol)
- Epimestrol
- Equilenin
- Equilin
- ERA-63 (ORG-37663)
- Esterified estrogens
- Estetrol
- Estradiol
- Estramustine
- Estramustine phosphate
- Estrapronicate
- Estrazinol
- Estriol
- Estrofurate
- Estrogenic substances
- Estromustine
- Estrone
- Etamestrol (eptamestrol)
- Ethinylandrostenediol
- Ethinylestradiol
- Ethinylestriol
- Ethylestradiol
- Etynodiol
- Etynodiol diacetate
- Hexolame
- Hippulin
- Hydroxyestrone diacetate
- Lynestrenol
- Lynestrenol phenylpropionate
- Mestranol
- Methylestradiol
- Moxestrol
- Mytatrienediol
- Nilestriol
- Norethisterone
- Noretynodrel
- Orestrate
- Pentolame
- Prodiame
- Prolame
- Promestriene
- RU-16117
- Quinestradol
- Quinestrol
- Tibolone
- Nonsteroidal: (R,R)-THC
- (S,S)-THC
- 2,8-DHHHC
- β-LGND1
- β-LGND2 (GTx-878)
- AC-186
- Allenestrol
- Allenolic acid
- Benzestrol
- Bifluranol
- Bisdehydrodoisynolic acid
- Butestrol
- Carbestrol
- D-15414
- DCW234
- Diarylpropionitrile
- Dienestrol
- Diethylstilbestrol
- Dimestrol (dianisylhexene)
- Dimethylstilbestrol
- Doisynoestrol (fenocycline)
- Doisynolic acid
- Efavirenz
- Elacestrant
- ERB-196 (WAY-202196)
- Erteberel (SERBA-1, LY-500307)
- Estrobin (DBE)
- Fenestrel
- FERb 033
- Fosfestrol (diethylstilbestrol diphosphate)
- Furostilbestrol (diethylstilbestrol difuroate)
- GTx-758
- Hexestrol
- ICI-85966 (Stilbostat)
- M2613
- meso-Butestrol
- meso-Hexestrol
- Mestilbol
- Methallenestril
- Methestrol
- Methestrol dipropionate
- Paroxypropione
- Pentafluranol
- Phenestrol
- Prinaberel (ERB-041, WAY-202041)
- Propylpyrazoletriol
- Quadrosilan
- SC-3296
- SC-4289
- SERBA-2
- SKF-82,958
- Terfluranol
- Triphenylbromoethylene
- Triphenylchloroethylene
- Triphenyliodoethylene
- Triphenylmethylethylene (triphenylpropene)
- WAY-166818
- WAY-169916
- WAY-200070
- WAY-204688 (SIM-688)
- WAY-214156
- Unknown/unsorted: ERB-26
- ERA-45
- ERB-79
- ZK-283197
- Xenoestrogens: Anise-related (e.g., anethole, anol, dianethole, dianol, photoanethole)
- Chalconoids (e.g., isoliquiritigenin, phloretin, phlorizin (phloridzin), wedelolactone)
- Coumestans (e.g., coumestrol, psoralidin)
- Flavonoids (incl. 7,8-DHF, 8-prenylnaringenin, apigenin, baicalein, baicalin, biochanin A, calycosin, catechin, daidzein, daidzin, ECG, EGCG, epicatechin, equol, formononetin, glabrene, glabridin, genistein, genistin, glycitein, kaempferol, liquiritigenin, mirificin, myricetin, naringenin, penduletin, pinocembrin, prunetin, puerarin, quercetin, tectoridin, tectorigenin)
- Lavender oil
- Lignans (e.g., enterodiol, enterolactone, nyasol (cis-hinokiresinol))
- Metalloestrogens (e.g., cadmium)
- Pesticides (e.g., alternariol, dieldrin, endosulfan, fenarimol, HPTE, methiocarb, methoxychlor, triclocarban, triclosan)
- Phytosteroids (e.g., digitoxin (digitalis), diosgenin, guggulsterone)
- Phytosterols (e.g., β-sitosterol, campesterol, stigmasterol)
- Resorcylic acid lactones (e.g., zearalanone, α-zearalenol, β-zearalenol, zearalenone, zeranol (α-zearalanol), taleranol (teranol, β-zearalanol))
- Steroid-like (e.g., deoxymiroestrol, miroestrol)
- Stilbenoids (e.g., resveratrol, rhaponticin)
- Synthetic xenoestrogens (e.g., alkylphenols, bisphenols (e.g., BPA, BPF, BPS), DDT, parabens, PBBs, PHBA, phthalates, PCBs)
- Others (e.g., agnuside, rotundifuran)
|
---|
Mixed (SERMsTooltip Selective estrogen receptor modulators) | |
---|
Antagonists | |
---|
|
---|
GPERTooltip G protein-coupled estrogen receptor | Agonists | |
---|
Antagonists | |
---|
Unknown | |
---|
|
---|
|
|
---|
GRTooltip Glucocorticoid receptor | Agonists |
- Cortisol-like and related (16-unsubstituted): 3α,5α-Tetrahydrocorticosterone
- 5α-Dihydrocorticosterone
- 9α-Fluorocortisone (alfluorone)
- 11-Dehydrocorticosterone (11-oxocorticosterone, 17-deoxycortisone)
- 11-Deoxycorticosterone (desoxycortone, deoxycortone, desoxycorticosterone)
- 11-Deoxycortisol (cortodoxone, cortexolone)
- 21-Deoxycortisol
- Δ7-Prednisolone
- Amebucort
- Chloroprednisone
- Cloprednol
- Corticosterone
- Cortisol (hydrocortisone)
- Cortisone
- Deprodone
- Dichlorisone
- Difluprednate
- Endrisone (endrysone)
- Etiprednol
- Fludrocortisone (fludrocortone)
- Fluorometholone
- Fluperolone
- Fluprednisolone
- Halopredone
- Isoflupredone (9α-fluoroprednisolone)
- Loteprednol
- Mazipredone (depersolone)
- Medrysone
- Methylprednisolone
- Prebediolone
- Prednisolone
- Prednisone
- Pregnenolone
- Resocortol
- Tipredane
- Tixocortol
- Methasones and related (16-substituted): 16α-Methyl-11-oxoprednisolone
- Alclometasone
- Amelometasone
- Beclometasone (beclomethasone)
- Betamethasone (betametasone)
- Ciclometasone (ciclomethasone, cyclomethasone)
- Clobetasol
- Clobetasone
- Clocortolone
- Cloticasone
- Cormetasone (cormethasone)
- Descinolone
- Desoximetasone (desoxymethasone)
- Dexamethasone (dexametasone)
- Diflorasone
- Diflucortolone
- Dimesone
- Doxibetasol (doxybetasol)
- Fluclorolone
- Flumetasone (flumethasone)
- Fluocinolone
- Fluocortin
- Fluocortolone
- Fluprednidene (fluprednylidene)
- Fluticasone
- Halocortolone
- Halometasone
- Icometasone
- Isoprednidene
- Locicortolone (locicortone)
- Meclorisone
- Meprednisone (methylprednisone)
- Mometasone
- Paramethasone
- Prednylidene
- Rimexolone
- Ticabesone
- Timobesone
- Triamcinolone
- Ulobetasol (halobetasol)
- Vamorolone
- Cyclic ketals (16,17-cyclized): Acrocinonide (triamcinolone acroleinide)
- Amcinafal (triamcinolone pentanonide)
- Amcinafide (triamcinolone acetophenide)
- Amcinonide (triamcinolone acetate cyclopentanonide)
- Budesonide
- Ciclesonide
- Cicortonide
- Deflazacort (azacort)
- Descinolone acetonide
- Desonide (hydroxyprednisolone acetonide)
- Dexbudesonide
- Drocinonide
- Fluazacort
- Fluclorolone acetonide (flucloronide)
- Fludroxycortide (flurandrenolone, flurandrenolide)
- Flumoxonide
- Flunisolide
- Fluocinolone acetonide
- Formocortal
- Halcinonide
- Itrocinonide
- Rofleponide
- Tralonide
- Triamcinolone acetonide
- Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB)
- Triclonide
- Others/atypical (other expanded steroid ring systems, homosteroids, and non-pregnane steroids): Cortisuzol
- Cortivazol
- Domoprednate
- Naflocort
- Nicocortonide
- Nivacortol (nivazol)
- Oxisopred
- RU-26988
- RU-28362
- Non-corticosteroids with some glucocorticoid activity: 15β-Hydroxycyproterone acetate
- 17α-Hydroxyprogesterone
- Bromoketoprogesterone
- Chlormadinone acetate
- Cyproterone
- Cyproterone acetate
- Danazol
- Delmadinone acetate
- Desogestrel
- DU-41165
- Etonogestrel
- Flugestone
- Flugestone acetate (flurogestone acetate)
- Fluoromedroxyprogesterone acetate
- Fluoxymesterone
- Gestodene
- Medrogestone
- Medroxyprogesterone acetate
- Megestrol acetate
- Metribolone
- Norgestomet
- Osaterone acetate
- Progesterone
- Promegestone
- RU-2309
- Quingestrone
- Segesterone acetate (nestorone)
- Tetrahydrogestrinone
- Nonsteroidal glucocorticoids: AZD-5423
- GSK-9027
|
---|
Mixed (SEGRMsTooltip Selective glucocorticoid receptor agonists) | |
---|
Antagonists | |
---|
Others | |
---|
|
---|
|
|
---|
MRTooltip Mineralocorticoid receptor | |
---|
|
|
---|
PRTooltip Progesterone receptor | Agonists |
- Progesterone derivatives: 3β-Dihydroprogesterone
- 5α-Dihydroprogesterone
- 6α-Methylprogesterone
- 9α-Bromo-11-ketoprogesterone
- 11-Dehydroprogesterone
- 11-Deoxycorticosterone
- 16α-Hydroxyprogesterone
- 17α-Methyl-11-deoxycorticosterone acetate
- 20α-Dihydroprogesterone
- 20β-Dihydroprogesterone
- Dimepregnen
- Diosgenin
- P1-185
- Progesterone
- Progesterone 3-acetyl enol ether
- Quingestrone
- Retroprogesterone derivatives: 20α-Dihydrodydrogesterone
- 20α-Dihydrotrengestone
- DU-41164
- DU-41165
- Dydrogesterone
- Retroprogesterone
- Ro 6-3129
- Trengestone
- 17α-Substituted progesterone derivatives: 6α-Methyl-17α-bromoprogesterone
- 15β-Hydroxycyproterone acetate
- 16-Methylene-17α-hydroxyprogesterone acetate
- 17α-Bromoprogesterone
- 17α-Hydroxyprogesterone (hydroxyprogesterone)
- 17α-Methylprogesterone
- Acetomepregenol (mepregenol diacetate)
- Algestone
- Algestone acetonide
- Algestone acetophenide
- Anagestone
- Anagestone acetate
- Bromethenmadinone
- Bromethenmadinone acetate
- Butagest (buterol)
- Chlormadinone
- Chlormadinone acetate
- Chlormadinone caproate
- Chlormethenmadinone
- Chlormethenmadinone acetate
- Cismadinone
- Cismadinone acetate
- Clogestone
- Clogestone acetate
- Clomegestone
- Clomegestone acetate
- Cymegesolate
- Cyproterone acetate
- Delmadinone
- Delmadinone acetate
- Edogestrone
- Flugestone
- Flugestone acetate
- Fluorometholone
- Fluorometholone acetate
- Flumedroxone
- Flumedroxone acetate
- Fluoromedroxyprogesterone acetate
- Gestaclone
- Gestobutanoyl
- Haloprogesterone
- Hydromadinone
- Hydromadinone acetate
- Hydroxyprogesterone acetate
- Hydroxyprogesterone caproate (hydroxyprogesterone hexanoate)
- Hydroxyprogesterone heptanoate (hydroxyprogesterone enanthate)
- Hydroxyprogesterone heptanoate benzilic acid hydrazone
- Mecigestone (pentarane B)
- Medrogestone
- Medroxyprogesterone
- Medroxyprogesterone acetate
- Medroxyprogesterone caproate
- Megestrol
- Megestrol acetate
- Megestrol caproate
- Melengestrol
- Melengestrol acetate
- Methenmadinone
- Methenmadinone acetate
- Methenmadinone caproate
- Mometasone
- Mometasone furoate
- Osaterone
- Osaterone acetate
- Pentagestrone
- Pentagestrone acetate
- Pentarane A
- Proligestone
- Triamcinolone acetonide
- 19-Norprogesterone derivatives: 17α-Methyl-19-norprogesterone
- 18-Methylsegesterone acetate
- 19-Norprogesterone
- Amadinone
- Amadinone acetate
- Demegestone
- Fluoro ethyl norprogesterone
- Fluoro furanyl norprogesterone
- Gestadienol
- Gestadienol acetate
- Gestonorone acetate (gestronol acetate)
- Gestonorone caproate (gestronol hexanoate)
- Gestronol (gestonorone)
- Nomegestrol
- Nomegestrol acetate
- Norgestomet
- ORG-2058
- Oxogestone
- Oxogestone phenpropionate (xinogestone)
- Promegestone
- Segesterone
- Segesterone acetate (nestorone)
- Trimegestone
- Testosterone derivatives: Progestins: 6,6-Difluoronorethisterone
- 6,6-Difluoronorethisterone acetate
- 17α-Allyl-19-nortestosterone
- Allylestrenol
- Altrenogest
- Chloroethynylnorgestrel
- Cingestol
- Danazol
- Desogestrel
- Dienogest
- Ethinylandrostenediol
- Ethisterone
- Ethynerone
- Etonogestrel
- Etynodiol
- Etynodiol diacetate
- Gestodene
- Gestrinone
- Levonorgestrel
- Levonorgestrel esters (e.g., levonorgestrel butanoate)
- Lynestrenol
- Lynestrenol phenylpropionate
- Metynodiol
- Metynodiol diacetate
- Norelgestromin
- Norethisterone (norethindrone)
- Norethisterone esters (e.g., norethisterone acetate, norethisterone enanthate)
- Noretynodrel
- Norgesterone
- Norgestimate
- Norgestrel
- Norgestrienone
- Norvinisterone
- Oxendolone
- Quingestanol
- Quingestanol acetate
- Tibolone
- Tigestol
- Tosagestin; Anabolic–androgenic steroids: 11β-Methyl-19-nortestosterone
- 11β-Methyl-19-nortestosterone dodecylcarbonate
- 19-Nor-5-androstenediol
- 19-Nor-5-androstenedione
- 19-Nordehydroepiandrosterone
- Bolandiol
- Bolandiol dipropionate
- Bolandione
- Dimethisterone
- Dienedione
- Dienolone
- Dimethandrolone
- Dimethandrolone buciclate
- Dimethandrolone dodecylcarbonate
- Dimethandrolone undecanoate
- Dimethyldienolone
- Dimethyltrienolone
- Ethyldienolone
- Ethylestrenol (ethylnandrol)
- Methyldienolone
- Metribolone (R-1881)
- Methoxydienone (methoxygonadiene)
- Mibolerone
- Nandrolone
- Nandrolone esters (e.g., nandrolone decanoate, nandrolone phenylpropionate)
- Norethandrolone
- Normethandrone (methylestrenolone, normethandrolone, normethisterone)
- RU-2309
- Tetrahydrogestrinone
- Trenbolone (trienolone)
- Trenbolone esters (e.g., trenbolone acetate, trenbolone enanthate)
- Trendione
- Trestolone
- Trestolone acetate
- Spirolactone derivatives: Canrenoic acid
- Canrenone
- Drospirenone
- Mespirenone
- Potassium canrenoate
- Prorenone
- SC-5233 (spirolactone)
- SC-8109
- Spironolactone
- Spirorenone
- Nonsteroidal: 3,8-Dihydrodiligustilide
- LG-2527
- LG-100128
- Riligustilide
- RWJ-26819
- RWJ-49853
- RWJ-60130
- Tanaproget
- ZM-182345
- Unknown: ORG-47241
- ORG-201745
|
---|
Mixed (SPRMsTooltip Selective progesterone receptor modulators) | |
---|
Antagonists | |
---|
|
---|
mPRTooltip Membrane progesterone receptor (PAQRTooltip Progestin and adipoQ receptor) | |
---|
|
|